EP 2318379 A1 20110511 - METHOD FOR PREPARATION OF PIPERAZINDIONE DERIVATES
Title (en)
METHOD FOR PREPARATION OF PIPERAZINDIONE DERIVATES
Title (de)
VERFAHREN ZUR HERSTELLUNG VON PIPERAZINDION-DERIVATEN
Title (fr)
PROCÉDÉ DE FABRICATION DE DÉRIVÉS DE PIPÉRAZINE-DIONE
Publication
Application
Priority
- EP 2009059859 W 20090730
- EP 08162326 A 20080813
- EP 09781280 A 20090730
Abstract (en)
[origin: WO2010018067A1] Method for preparation of piperazindione derivates of formula I, wherein R1 stands for hydrogen, alkyl, alkenyl, alkinyl and alkylcarbonyl, R2 stands for hydrogen, alkyl, alkenyl, C3-C4-alkinyl and C(=O)R11, R3,R4 stand for hydrogen, alkyl and halogen-alkyl, wherein the groups can be substituted, characterized in that amines of formula II, in which R1 stands for hydrogen and alkyl, which likewise can be substituted, are reacted under basic conditions in an aqueous solvent with N-acylated amino acid derivates of formula II, wherein X stands for halogen, Y halogen, alkoxy or phenyloxy, which can be substituted, and R2, R3 and R4 have the meaning above.
IPC 8 full level
C07D 241/08 (2006.01)
CPC (source: EP US)
C07D 241/08 (2013.01 - EP US)
Citation (search report)
See references of WO 2010018067A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
Designated extension state (EPC)
AL BA RS
DOCDB simple family (publication)
WO 2010018067 A1 20100218; AR 073036 A1 20101006; BR PI0916949 A2 20150818; CN 102119153 A 20110706; EP 2318379 A1 20110511; JP 2011530559 A 20111222; US 2011144336 A1 20110616
DOCDB simple family (application)
EP 2009059859 W 20090730; AR P090103121 A 20090812; BR PI0916949 A 20090730; CN 200980130668 A 20090730; EP 09781280 A 20090730; JP 2011522466 A 20090730; US 200913058677 A 20090730