Global Patent Index - EP 2331705 A1

EP 2331705 A1 20110615 - LGR5 MODULATORS IN THE TREATMENT OF ALOPECIA

Title (en)

LGR5 MODULATORS IN THE TREATMENT OF ALOPECIA

Title (de)

LGR5-MODULATOREN BEI DER BEHANDLUNG VON HAARAUSFALL

Title (fr)

MODULATEURS DE LGR5 DANS LE TRAITEMENT DE L'ALOPECIE

Publication

EP 2331705 A1 20110615 (FR)

Application

EP 09747891 A 20090921

Priority

  • FR 2009051771 W 20090921
  • FR 0856316 A 20080919

Abstract (en)

[origin: WO2010031980A1] The invention relates to an in vitro method of screening for candidate compounds for the preventive or curative treatment of alopecia, which comprises determining the ability of a compound to modulate the expression or the activity of the LGR5 receptor, and also to the use of modulators of the expression or of the activity of this receptor for treating alopecia. The invention also relates to methods for the diagnosis or prognosis, in vitro, of this disease.

IPC 8 full level

C12Q 1/68 (2006.01)

CPC (source: EP US)

C12Q 1/6883 (2013.01 - EP US); C12Q 2600/136 (2013.01 - EP US); C12Q 2600/158 (2013.01 - EP US)

Citation (search report)

See references of WO 2010031980A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

Designated extension state (EPC)

AL BA RS

DOCDB simple family (publication)

FR 2936256 A1 20100326; FR 2936256 B1 20100910; CA 2738002 A1 20100325; EP 2331705 A1 20110615; US 2011236893 A1 20110929; WO 2010031980 A1 20100325

DOCDB simple family (application)

FR 0856316 A 20080919; CA 2738002 A 20090921; EP 09747891 A 20090921; FR 2009051771 W 20090921; US 200913120104 A 20090921