EP 2344179 A1 20110720 - Insulin-like growth factor binding protein 7 (IGFBP7) and pharmaceutical compositions thereof for use in the treatment of a pathology characterized by hyperproliferative keratinocytes
Title (en)
Insulin-like growth factor binding protein 7 (IGFBP7) and pharmaceutical compositions thereof for use in the treatment of a pathology characterized by hyperproliferative keratinocytes
Title (de)
Zusammensetzungen Insulin-ähnlicher Wachstumsfaktor-Bindungsproteine 7 (IGFBP7) enthaltend zur Verwendung bei der Behandlung einer Pathologie gekennzeichnet durch hyperproliferative Keratinozyten
Title (fr)
Compositions comprenant le facteur de croissance insuline-like protein 7 (IGFBP7) pour son utilisation dans la traitement d'une pathologie caractérisée par une hyperprolifération des kératinocytes
Publication
Application
Priority
- IL 2010000167 W 20100228
- US 20276009 P 20090401
Abstract (en)
[origin: WO2010113146A1] Provided are methods of regulating keratinocytes proliferation and differentiation by subjecting keratinocytes to an agent capable of modulating activity or expression of IGFBP7, thereby regulating keratinocytes proliferation and differentiation. Also provided are methods of treating pathologies characterized by hyperproliferative keratinocytes by administering IGFBP7 polypeptide or a polynucleotide encoding IGFBP7 polypeptide to a subject.
IPC 8 full level
A61K 38/17 (2006.01); A61P 17/00 (2006.01); A61P 17/06 (2006.01)
CPC (source: EP US)
A61K 38/1703 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61P 17/00 (2017.12 - EP); A61P 17/06 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 37/08 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Citation (search report)
See references of WO 2010113146A1
Citation (examination)
- WO 2007039255 A1 20070412 - UNIV MAASTRICHT [NL], et al
- WO 2009036188 A2 20090319 - UNIV MASSACHUSETTS [US], et al
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
Designated extension state (EPC)
AL BA RS
DOCDB simple family (publication)
WO 2010113146 A1 20101007; AU 2010231514 A1 20111103; CA 2759201 A1 20101007; CN 102448484 A 20120509; EP 2344179 A1 20110720; JP 2012522762 A 20120927; MX 2011010401 A 20120120; US 2011207665 A1 20110825; US 8912142 B2 20141216
DOCDB simple family (application)
IL 2010000167 W 20100228; AU 2010231514 A 20100228; CA 2759201 A 20100228; CN 201080024052 A 20100228; EP 10710105 A 20100228; JP 2012502872 A 20100228; MX 2011010401 A 20100228; US 201013127058 A 20100228