EP 2344499 A1 20110720 - NOVEL NITROGENOUS HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF AND USE THEREOF AS ANTIBACTERIAL MEDICAMENTS
Title (en)
NOVEL NITROGENOUS HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF AND USE THEREOF AS ANTIBACTERIAL MEDICAMENTS
Title (de)
NEUE, STICKSTOFFHALTIGE HETEROCYCLISCHE VERBINDUNGEN, DEREN HERSTELLUNG UND DEREN VERWENDUNG ALS ANTIBAKTERIELLE MEDIKAMENTE
Title (fr)
NOUVEAUX COMPOSES HETEROCYCLIQUES AZOTES, LEUR PRÉPARATION ET LEUR UTILISATION COMME MÉDICAMENTS ANTIBACTÉRIENS
Publication
Application
Priority
- IB 2009006433 W 20090803
- FR 0805472 A 20081003
Abstract (en)
[origin: WO2010038115A1] The invention relates to nitrogenous heterocyclic compounds of general formula (I) in which: R1 is a (CH2)n-NH2 radical, n being equal to 1 or 2; R2 is a hydrogen atom; R3 and R4 together form a nitrogenous heterocycle that is aromatic in nature, with 5 ring members, containing 1, 2 or 3 nitrogen atoms, substituted on this nitrogen atom or on one of these nitrogen atoms with a (CH2)m-(C(O))P-R5 group, m being equal to 0, 1, 2 or 3, p being equal to 0 or 1 and R5 being a hydroxyl group, in which case p is equal to 1, or an amino, (C1-C6)alkyl OR (C1-C6)dialkyl amino group, or a nitrogenous heterocycle that is aromatic in nature, with 5 or 6 ring members, containing one or two nitrogen atoms and, where appropriate, an oxygen or sulphur atom; it being understood that, when the (C(O))P-R5 subgroup forms a carboxyl, amino, (C1-C6)alkyl or (C1-C6)dialkyl amino group, m is other than 0 or 1; in free form or in the form of zwitterions or of salts with inorganic or organic bases and acids which are pharmaceutically acceptable, to the preparation thereof and to the use thereof as antibacterial medicaments.
IPC 8 full level
C07D 471/18 (2006.01); A61K 31/437 (2006.01); A61P 31/04 (2006.01)
CPC (source: EP KR US)
A61K 31/437 (2013.01 - KR); A61P 31/04 (2017.12 - EP); C07D 471/08 (2013.01 - KR); C07D 471/18 (2013.01 - EP KR US)
Citation (search report)
See references of WO 2010038115A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
Designated extension state (EPC)
AL BA RS
DOCDB simple family (publication)
WO 2010038115 A1 20100408; AU 2009299511 A1 20100408; BR PI0919810 A2 20171031; BR PI0919810 A8 20171212; CA 2739503 A1 20100408; CL 2011000729 A1 20120706; CN 102203094 A 20110928; CN 102203094 B 20140402; CO 6361957 A2 20120120; EA 021799 B1 20150930; EA 201170522 A1 20111230; EC SP11010946 A 20110531; EP 2344499 A1 20110720; EP 2845855 A1 20150311; FR 2936798 A1 20100409; FR 2936798 B1 20120928; IL 212059 A0 20110630; JP 2012504593 A 20120223; JP 5555240 B2 20140723; KR 20110067137 A 20110621; MX 2011003573 A 20110812; PE 20110845 A1 20111117; US 2010087648 A1 20100408; US 8067435 B2 20111129; ZA 201102429 B 20120530
DOCDB simple family (application)
IB 2009006433 W 20090803; AU 2009299511 A 20090803; BR PI0919810 A 20090803; CA 2739503 A 20090803; CL 2011000729 A 20110401; CN 200980141781 A 20090803; CO 11040684 A 20110401; EA 201170522 A 20090803; EC SP11010946 A 20110401; EP 09786093 A 20090803; EP 14188601 A 20090803; FR 0805472 A 20081003; IL 21205911 A 20110331; JP 2011529643 A 20090803; KR 20117009615 A 20090803; MX 2011003573 A 20090803; PE 2011000827 A 20090803; US 53609609 A 20090805; ZA 201102429 A 20110330