EP 2344656 A1 20110720 - MICROORGANISM FOR PRODUCING SUCCINIC ACID
Title (en)
MICROORGANISM FOR PRODUCING SUCCINIC ACID
Title (de)
MIKROORGANISMUS ZUR HERSTELLUNG VON BERNSTEINSÄURE
Title (fr)
MICRO-ORGANISME PERMETTANT DE PRODUIRE DE L'ACIDE SUCCINIQUE
Publication
Application
Priority
- DE 2009001386 W 20091007
- DE 102008051727 A 20081017
Abstract (en)
[origin: WO2010043197A1] The invention relates to an isolated, genetically modified microorganism, wherein compared to the wild type a) the idh1 and idp1 genes have been deleted or inactivated, and/or b) the sdh2 and sdh1 genes have been deleted or inactivated, and/or c) the PDC2 gene has been deleted or inactivated or is under the control of a promoter which can be suppressed or induced by exposure of the microorganism using an inductor substance, and/or d) one or more genes from the group consisting of ICL1, MLS1, ACS1 and MDH3 has been replaced or supplemented by a corresponding foreign gene or corresponding foreign genes from Crabtree-negative organisms, and to the uses thereof.
IPC 8 full level
C12P 7/46 (2006.01); C12N 1/18 (2006.01); C12N 9/04 (2006.01); C12R 1/865 (2006.01)
CPC (source: EP KR US)
C12N 1/18 (2013.01 - KR); C12N 9/0006 (2013.01 - EP US); C12N 9/001 (2013.01 - EP US); C12N 9/1025 (2013.01 - EP US); C12N 9/88 (2013.01 - EP US); C12N 9/93 (2013.01 - EP US); C12P 7/46 (2013.01 - EP KR US); C12Y 101/01037 (2013.01 - EP US); C12Y 101/01042 (2013.01 - EP US); C12Y 103/05001 (2013.01 - EP US); C12Y 203/03009 (2013.01 - EP US); C12Y 401/03001 (2013.01 - EP US); C12Y 602/01001 (2013.01 - EP US)
Citation (search report)
See references of WO 2010043197A1
Citation (examination)
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; 5 June 1993 (1993-06-05), HASELBECK R J ET AL: "Function and expression of yeast mitochondrial NAD- and NADP-specific isocitrate dehydrogenases.", Database accession no. NLM8099357 & HASELBECK R J ET AL: "Function and expression of yeast mitochondrial NAD- and NADP-specific isocitrate dehydrogenases.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 5 JUN 1993 LNKD- PUBMED:8099357, vol. 268, no. 16, 5 June 1993 (1993-06-05), pages 12116 - 12122, ISSN: 0021-9258
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
Designated extension state (EPC)
AL BA RS
DOCDB simple family (publication)
DE 102008051727 A1 20100422; BR PI0919826 A2 20150818; CN 102257152 A 20111123; EP 2344656 A1 20110720; JP 2012505638 A 20120308; KR 20110071128 A 20110628; RU 2011119763 A 20121127; US 2011300595 A1 20111208; WO 2010043197 A1 20100422; ZA 201103570 B 20120125
DOCDB simple family (application)
DE 102008051727 A 20081017; BR PI0919826 A 20091007; CN 200980151009 A 20091007; DE 2009001386 W 20091007; EP 09748218 A 20091007; JP 2011531347 A 20091007; KR 20117011224 A 20091007; RU 2011119763 A 20091007; US 200913124436 A 20091007; ZA 201103570 A 20110516