EP 2347730 A1 20110727 - Methods and compositions for delivery of growth factor to fibrous connective tissue
Title (en)
Methods and compositions for delivery of growth factor to fibrous connective tissue
Title (de)
Verfahren und Zusammensetzungen zur Wachstumsfaktorfreisetzung an fasriges Bindegewebe
Title (fr)
Procédés et compositions pour la fourniture de facteur de croissance de tissu conjonctif fibreux
Publication
Application
Priority
- EP 08799183 A 20080904
- US 96974807 P 20070904
Abstract (en)
The presently disclosed subject matter relates to a peptide composition for non-covalently localizing fibrous connective tissue-inducing growth factor to a surface of an implant, the composition comprising a peptide having binding affinity for a surface material of an implant coupled to a peptide having binding affinity for a fibrous connective tissue-inducing growth factor. Methods are provided for delivering fibrous connective tissue-inducing growth factor GDF-7 in an amount effective to promote fibrous connective tissue repair and fibrous connective tissue formation. Also provided are methods of applying the peptide composition to an implant by contacting the composition with a surface of the implant; and kits comprising the compositions.
IPC 8 full level
A61F 2/02 (2006.01); A61K 38/04 (2006.01)
CPC (source: EP US)
A61K 9/0024 (2013.01 - EP US); A61L 27/227 (2013.01 - EP US); A61L 27/54 (2013.01 - EP US); A61P 19/04 (2017.12 - EP); C07K 14/71 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US); A61L 2300/25 (2013.01 - EP US); A61L 2300/414 (2013.01 - EP US); A61L 2300/606 (2013.01 - EP US); C07K 2319/20 (2013.01 - EP US)
Citation (applicant)
- US 969748 P
- US 7252832 B1 20070807 - STONE KEVIN T [US], et al
Citation (search report)
- [A] US 2004127640 A1 20040701 - BELCHER ANGELA M [US], et al
- [A] US 2004127696 A1 20040701 - LEE SE-JIN [US], et al
- [E] WO 2009120968 A2 20091001 - AFFINERGY INC [US], et al
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2009032943 A2 20090312; WO 2009032943 A3 20091230; CN 101827564 A 20100908; EP 2182888 A2 20100512; EP 2182888 A4 20100908; EP 2347730 A1 20110727; US 2009098175 A1 20090416; US 8067021 B2 20111129
DOCDB simple family (application)
US 2008075282 W 20080904; CN 200880105374 A 20080904; EP 08799183 A 20080904; EP 11155764 A 20080904; US 20473108 A 20080904