EP 2351848 A4 20160817 - METHOD FOR PRODUCING L-AMINO ACID
Title (en)
METHOD FOR PRODUCING L-AMINO ACID
Title (de)
VERFAHREN ZUR HERSTELLUNG VON L-AMINOSÄURE
Title (fr)
PROCÉDÉ POUR LA FABRICATION D'UN ACIDE AMINÉ L
Publication
Application
Priority
- JP 2009068515 W 20091028
- JP 2008277674 A 20081029
Abstract (en)
[origin: EP2351848A1] The present invention relates to a method for producing an L-amino acid by reacting an enantiomeric mixture of an N-succinyl amino acid with L-succinylase in the presence of N-acylamino acid racemase to specifically hydrolyze the L-form. In particular, the present invention relates to a method for producing an L-amino acid in high yield by using an N-succinyl amino acid whose dissolved concentration is particularly low as a raw material to perform a reaction while precipitating the produced L-amino acid out of the reaction system. The present invention enables efficient production of an L-amino acid having high optical purity, particularly an L-amino acid useful as a raw material for products such as pharmaceutical products and agricultural chemicals.
IPC 8 full level
C12P 41/00 (2006.01); C07C 233/47 (2006.01); C12N 15/09 (2006.01)
CPC (source: EP US)
C07C 227/30 (2013.01 - EP US); C07C 233/47 (2013.01 - EP US); C12N 9/104 (2013.01 - EP US); C12N 9/90 (2013.01 - EP US); C12P 13/04 (2013.01 - EP US); C12P 13/222 (2013.01 - EP US); C12P 41/007 (2013.01 - EP US); Y02P 20/52 (2015.11 - US)
Citation (search report)
- [A] EP 1197563 A1 20020417 - DEGUSSA [DE]
- [X] AYANO SAKAI ET AL: "Evolution of Enzymatic Activities in the Enolase Superfamily: N-Succinylamino Acid Racemase and a New Pathway for the Irreversible Conversion Of D- to L-Amino Acids", BIOCHEMISTRY, vol. 45, no. 14, 1 April 2006 (2006-04-01), pages 4455 - 4462, XP055131382, ISSN: 0006-2960, DOI: 10.1021/bi060230b
- See references of WO 2010050516A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
DOCDB simple family (publication)
EP 2351848 A1 20110803; EP 2351848 A4 20160817; EP 2351848 B1 20180228; CN 102203274 A 20110928; CN 102203274 B 20170405; JP 2015091265 A 20150514; JP 5744521 B2 20150708; JP 6039710 B2 20161207; JP WO2010050516 A1 20120329; SG 10201400650Q A 20140529; US 2011229940 A1 20110922; US 9464306 B2 20161011; WO 2010050516 A1 20100506
DOCDB simple family (application)
EP 09823626 A 20091028; CN 200980143175 A 20091028; JP 2009068515 W 20091028; JP 2010535820 A 20091028; JP 2015013526 A 20150127; SG 10201400650Q A 20091028; US 200913126534 A 20091028