EP 2356215 A1 20110817 - SUBSTRATE FOR SELECTING AND SPECIFICALLY INFLUENCING THE FUNCTION OF CELLS
Title (en)
SUBSTRATE FOR SELECTING AND SPECIFICALLY INFLUENCING THE FUNCTION OF CELLS
Title (de)
SUBSTRATE ZUR SELEKTION UND SPEZIFISCHEN BEEINFLUSSUNG DER FUNKTION VON ZELLEN
Title (fr)
SUBSTRATS PERMETTANT DE SÉLECTIONNER ET D'INFLUENCER SPÉCIFIQUEMENT LE FONCTIONNEMENT DE CELLULES
Publication
Application
Priority
- EP 2009008723 W 20091207
- DE 102008060991 A 20081208
Abstract (en)
[origin: WO2010075933A1] The invention relates to a method and to a substrate for selecting and specifically influencing the function of cells by the adhesion thereof to substrate surfaces having prescribed properties. Said substrates comprise various surface regions each representing a condition affecting the cell adhesion and/or cell function, and said conditions are determined by a geometric property and/or a mechanical property or a combination of a geometric property and/or a mechanical property with a chemical property of each surface region. The invention further relates to analysis devices and to analysis methods using said substrates for identifying and selecting particular cell types, for identifying suitable substrate conditions for affecting a particular cell function or particular cell type or for identifying disease states characterized by a change in the cell type or cell function.
IPC 8 full level
C12N 5/00 (2006.01); G01N 33/50 (2006.01)
CPC (source: EP US)
C12N 5/0068 (2013.01 - EP US); G01N 33/502 (2013.01 - EP US); G01N 33/54393 (2013.01 - EP US); G01N 33/552 (2013.01 - EP US); C12N 2533/40 (2013.01 - EP US); C12N 2533/52 (2013.01 - EP US); C12N 2533/54 (2013.01 - EP US); C12N 2535/10 (2013.01 - EP US)
Citation (examination)
ARNOLD M ET AL: "Induction of cell polarization and migration by a gradient of nanoscale variations in adhesive ligand spacing", NANO LETTERS, AMERICAN CHEMICAL SOCIETY, US, vol. 8, no. 7, 9 July 2008 (2008-07-09), pages 2063 - 2069, XP002576946, ISSN: 1530-6984, [retrieved on 20080618], DOI: 10.1021/NL801483W
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
DOCDB simple family (publication)
DE 102008060991 A1 20100610; CN 102317441 A 20120111; EP 2356215 A1 20110817; US 2011275539 A1 20111110; WO 2010075933 A1 20100708
DOCDB simple family (application)
DE 102008060991 A 20081208; CN 200980154213 A 20091207; EP 09764742 A 20091207; EP 2009008723 W 20091207; US 200913133087 A 20091207