Global Patent Index - EP 2358369 A1

EP 2358369 A1 20110824 - Process for the preparation of substantially optically pure repaglinide and precursors thereof

Title (en)

Process for the preparation of substantially optically pure repaglinide and precursors thereof

Title (de)

VERFAHREN ZUR HERSTELLUNG VON WEITGEHEND OPTISCH REINEM REPAGLINID UND VORSTUFEN DAVON

Title (fr)

Procédé de synthèse de répaglinide substantiellement optiquement pure et de ses précurseurs

Publication

EP 2358369 A1 20110824 (EN)

Application

EP 09737422 A 20091020

Priority

  • EP 2009063734 W 20091020
  • EP 08167069 A 20081020
  • EP 08173072 A 20081230
  • EP 09154353 A 20090304
  • EP 09737422 A 20091020

Abstract (en)

[origin: WO2010046360A1] The invention relates to a process for preparing substantially optically pure repaglinide and pharmaceutically acceptable salts, solvates and esters thereof. The invention further relates to a process for preparing precursors of repaglinide and in particular for preparing ( S ) ( f ) - 1 - ( 2 -piperidino-phenyl ) -3 - methyl - I -butylamine.

IPC 8 full level

A61K 31/4453 (2006.01); A61P 5/50 (2006.01); C07D 295/135 (2006.01)

CPC (source: EP)

A61P 5/50 (2017.12); C07D 295/135 (2013.01)

Citation (search report)

See references of WO 2010046360A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

Designated extension state (EPC)

AL BA RS

DOCDB simple family (publication)

WO 2010046360 A1 20100429; EP 2358369 A1 20110824

DOCDB simple family (application)

EP 2009063734 W 20091020; EP 09737422 A 20091020