EP 2376661 A1 20111019 - SIMULTANEOUS DETERMINATION OF ANEUPLOIDY AND FETAL FRACTION
Title (en)
SIMULTANEOUS DETERMINATION OF ANEUPLOIDY AND FETAL FRACTION
Title (de)
GLEICHZEITIGE BESTIMMUNG VON ANEUPOLIDIE- UND FÖTUS-DNA-FRAKTIONEN
Title (fr)
DÉTERMINATION SIMULTANÉE DE L'ANEUPLOÏDIE ET DE LA FRACTION FOETALE
Publication
Application
Priority
- US 2010058612 W 20101201
- US 29635810 P 20100119
- US 36083710 P 20100701
- US 40701710 P 20101026
- US 45584910 P 20101026
Abstract (en)
[origin: US2011201507A1] The invention provides methods for determining aneuploidy and/or fetal fraction in maternal samples comprising fetal and maternal cfDNA by massively parallel sequencing. The method comprises a novel protocol for preparing sequencing libraries that unexpectedly improves the quality of library DNA while expediting the process of analysis of samples for prenatal diagnoses.
IPC 8 full level
C12Q 1/68 (2006.01); C12P 19/34 (2006.01)
CPC (source: EP GB US)
C12Q 1/68 (2013.01 - GB); C12Q 1/6806 (2013.01 - EP GB US); C12Q 1/6809 (2013.01 - EP US); C12Q 1/6827 (2013.01 - GB); C12Q 1/6869 (2013.01 - EP GB US); C12Q 1/6872 (2013.01 - GB); C12Q 1/6883 (2013.01 - GB); C40B 30/00 (2013.01 - GB); G16B 20/10 (2019.02 - US); G16B 30/00 (2019.02 - GB); G16B 30/10 (2019.02 - US); G16B 99/00 (2019.02 - GB); G16H 10/40 (2018.01 - US); C12Q 1/6883 (2013.01 - EP US); C12Q 2545/101 (2013.01 - GB); C12Q 2600/106 (2013.01 - EP US); C12Q 2600/112 (2013.01 - US)
C-Set (source: EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
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DOCDB simple family (application)
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