EP 2379539 A1 20111026 - AMINO ACID ESTER PRODRUGS AND THE USE THEREOF
Title (en)
AMINO ACID ESTER PRODRUGS AND THE USE THEREOF
Title (de)
AMINOSÄUREESTER-PRODRUGS UND IHRE VERWENDUNG
Title (fr)
PROMÉDICAMENTS D'ESTERS D'ACIDES AMINÉS ET LEUR UTILISATION
Publication
Application
Priority
- EP 2009008618 W 20091203
- DE 102008062566 A 20081216
Abstract (en)
[origin: CA2746727A1] The invention relates to amino acid ester prodrug derivatives of 2-amino-6-({[2-(4-chlorphenyl)-1,3-oxazol-4-yl]methyl}sulfanyl)4-(4-{[2,3-dihydroxypropyl]oxy}phenyl)pyridine- 3,5-dicarbonitriles of formula (I), where RA is hydrogen or methyl, and RPD is a group of the formulas (II) or (III), wherein # is the linking site having each O atom, to a method for the production thereof, to the use thereof for treating and/or preventing illnesses, and to the use thereof for producing pharmaceuticals for treating and/or preventing illnesses, particularly of cardiovascular diseases.
IPC 8 full level
C07D 413/12 (2006.01); A61K 31/4439 (2006.01)
CPC (source: EP US)
A61K 31/4439 (2013.01 - EP US); A61P 9/00 (2017.12 - EP); A61P 9/04 (2017.12 - EP); A61P 9/06 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 413/12 (2013.01 - EP US)
Citation (search report)
See references of WO 2010072315A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
DOCDB simple family (publication)
DE 102008062566 A1 20100617; CA 2746727 A1 20100701; EP 2379539 A1 20111026; JP 2012512203 A 20120531; US 2011237629 A1 20110929; WO 2010072315 A1 20100701
DOCDB simple family (application)
DE 102008062566 A 20081216; CA 2746727 A 20091203; EP 09760499 A 20091203; EP 2009008618 W 20091203; JP 2011541148 A 20091203; US 200913132989 A 20091203