EP 2391372 A4 20130703 - METHODS FOR TREATING ESTROGEN RECEPTOR POSITIVE CANCER BY X-BOX BINDING PROTEIN 1 INHIBITION
Title (en)
METHODS FOR TREATING ESTROGEN RECEPTOR POSITIVE CANCER BY X-BOX BINDING PROTEIN 1 INHIBITION
Title (de)
VERFAHREN ZUR BEHANDLUNG VON ÖSTROGENREZEPTOR-POSITIVEM TUMOR MITTELS HEMMUNG DES X-BOX-BINDENDEN PROTEINS 1
Title (fr)
MÉTHODES DE TRAITEMENT DE CANCER POSITIF AUX RÉCEPTEURS OESTROGÉNIQUES PAR INHIBITION DE LA PROTÉINE DE LIAISON À LA BOÎTE X 1 (XBP1)
Publication
Application
Priority
- US 2010022552 W 20100129
- US 14851809 P 20090130
Abstract (en)
[origin: WO2010088498A1] Provided is a method of inhibiting proliferation of estrogen receptor alpha positive tumor cells comprising the inhibition of X-box binding protein-1 (Xbp1), including inhibiting estrogen-induced proliferation.
IPC 8 full level
A61K 31/70 (2006.01); A61K 31/00 (2006.01); A61K 31/7088 (2006.01); A61K 35/12 (2006.01); A61K 39/395 (2006.01); C12N 15/113 (2010.01)
CPC (source: EP)
A61K 31/00 (2013.01); A61K 31/70 (2013.01); A61P 35/00 (2017.12); C12N 15/113 (2013.01); C12N 2310/14 (2013.01)
Citation (search report)
- [X] WO 2004020610 A2 20040311 - HARVARD COLLEGE [US]
- [X] WO 2007101224 A2 20070907 - UNIV LELAND STANFORD JUNIOR [US], et al
- [I] B. P. GOMEZ ET AL: "Human X-Box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines", THE FASEB JOURNAL, vol. 21, no. 14, 20 July 2007 (2007-07-20), pages 4013 - 4027, XP055061962, ISSN: 0892-6638, DOI: 10.1096/fj.06-7990com
- See references of WO 2010088498A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
DOCDB simple family (publication)
WO 2010088498 A1 20100805; CA 2749947 A1 20100805; EP 2391372 A1 20111207; EP 2391372 A4 20130703
DOCDB simple family (application)
US 2010022552 W 20100129; CA 2749947 A 20100129; EP 10736464 A 20100129