Global Patent Index - EP 2403830 A2

EP 2403830 A2 20120111 - INDOLE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES

Title (en)

INDOLE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES

Title (de)

INDOLDERIVATE ZUR BEHANDLUNG NEURODEGENERATIVER KRANKHEITEN

Title (fr)

DERIVES INDOLIQUES POUR LE TRAITEMENT DE MALADIES NEURODEGENERATIVES

Publication

EP 2403830 A2 20120111 (FR)

Application

EP 10705616 A 20100302

Priority

  • EP 2010052596 W 20100302
  • FR 0951303 A 20090302

Abstract (en)

[origin: WO2010100133A2] The invention relates to a compound of the following formula (I), or to a pharmaceutically acceptable salt thereof or to a stereoisomer or mixture of stereoisomers at any proportions, where: X1 is a CH2 or C=O group; X2 is a linear saturated or unsaturated carbohydrate chain with 8 to 24 carbon atoms; R1 is a hydrogen atom or an OH or (C1-C6)alkoxy group such as methoxy; and R2 is a CH3 or CH2OR3 group, with R3 being a hydrogen atom or a (C1-C6)alkyl, CO-(C1-C6)alkyl or NH-(C1-C6)alkyl group. The invention also relates to the use of said compound as a drug, in particular for treating neurodegenerative diseases, and to a method for preparing same.

IPC 8 full level

C07D 209/16 (2006.01); A61K 31/4045 (2006.01); A61P 25/28 (2006.01)

CPC (source: EP US)

A61P 25/00 (2017.12 - EP); A61P 25/16 (2017.12 - EP); A61P 25/28 (2017.12 - EP); C07D 209/16 (2013.01 - EP US)

Citation (search report)

See references of WO 2010100133A2

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

DOCDB simple family (publication)

FR 2942625 A1 20100903; FR 2942625 B1 20131122; CA 2754283 A1 20100910; CN 102369185 A 20120307; EP 2403830 A2 20120111; JP 2012519202 A 20120823; US 2011319387 A1 20111229; US 8614246 B2 20131224; WO 2010100133 A2 20100910; WO 2010100133 A3 20101118

DOCDB simple family (application)

FR 0951303 A 20090302; CA 2754283 A 20100302; CN 201080014716 A 20100302; EP 10705616 A 20100302; EP 2010052596 W 20100302; JP 2011552413 A 20100302; US 201013254370 A 20100302