EP 2405755 A4 20121128 - METHODS AND COMPOSITIONS FOR THE TREATMENT OF METABOLIC AND CARDIOVASCULAR DISORDERS
Title (en)
METHODS AND COMPOSITIONS FOR THE TREATMENT OF METABOLIC AND CARDIOVASCULAR DISORDERS
Title (de)
VERFAHREN UND ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON STOFFWECHSEL- UND HERZ-KREISLAUF-ERKRANKUNGEN
Title (fr)
MÉTHODES ET COMPOSITIONS UTILISÉES POUR LE TRAITEMENT DE MALADIES MÉTABOLIQUES ET CARDIOVASCULAIRES
Publication
Application
Priority
- US 2010000750 W 20100311
- US 15942909 P 20090311
- US 15942309 P 20090311
- US 15942709 P 20090311
Abstract (en)
[origin: WO2010104595A1] Methods and compositions containing a berberine related compound are provided for the prevention and treatment of metabolic and cardiovascular disorders including metabolic syndrome, hyperlipidemia, obesity, diabetes, insulin resistance, hyperglycemia, hypertension and elevated cholesterol in mammalian subjects. The methods and compositions of the invention are effective for prevention and treatment of metabolic syndrome, hyperlipidemia, obesity, diabetes, insulin resistance, hyperglycemia, hypertension and elevated cholesterol. Additional compositions and methods are provided which employ a berberine related or derivative compound including demethylated derivatives in combination with a second anti- therapeutic agent to yield more effective treatment tools against metabolic disorders, and/or dual activity therapeutic methods and formulations useful to prevent or reduce hyperlipidemia and/or hyperglycemia and one or more causal or related symptoms or conditions associated with hyperlipidemia and/or hyperglycemia in mammalian subjects.
IPC 8 full level
A61K 31/4741 (2006.01); A61K 45/06 (2006.01); A61P 3/04 (2006.01); A61P 3/06 (2006.01); A61P 3/10 (2006.01); A61P 9/12 (2006.01)
CPC (source: EP)
A61K 31/4741 (2013.01); A61K 45/06 (2013.01); A61P 3/04 (2017.12); A61P 3/06 (2017.12); A61P 3/10 (2017.12); A61P 9/12 (2017.12)
Citation (search report)
- [X] WO 2006029577 A1 20060323 - EMY OF MEDICAL SCIENCES INST O [CN], et al
- [X] WO 2007113748 A1 20071011 - ROTTAPHARM SPA [IT], et al
- [X] WO 8303970 A1 19831124 - MAROKO PETER R
- [A] WO 2004032924 A1 20040422 - JIANG JIANDONG [CN], et al
- [A] WO 0195908 A1 20011220 - HANWHA CHEMICAL CORP [KR], et al
- See references of WO 2010104595A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
DOCDB simple family (publication)
WO 2010104595 A1 20100916; EP 2405755 A1 20120118; EP 2405755 A4 20121128
DOCDB simple family (application)
US 2010000750 W 20100311; EP 10751135 A 20100311