EP 2407156 A3 20120711 - Aqueous coacervate compositions suitable for making powders and water-soluble formulations of biologically-active agents
Title (en)
Aqueous coacervate compositions suitable for making powders and water-soluble formulations of biologically-active agents
Title (de)
Wässrige Koazervatzusammensetzungen zur Herstellung von Pulver und wasserlöslichen Formulierungen biologischer Wirkstoffe
Title (fr)
Compositions coacervatées aqueuses adaptées à la fabrication de poudres et formulations solubles dans l'eau d'agents actifs biologiques
Publication
Application
Priority
GB 201011821 A 20100714
Abstract (en)
[origin: EP2407156A2] This invention relates to an aqueous gel-free two-phase coacervate composition comprising a coacervate phase and an equilibrium water phase, comprising a mixture of: (a) a poorly water-soluble bio-active agent, (b) a tensio-active system with a HLB from 8 to 18 and consisting of non-ionic tensio-active agents, (c) one or more water-soluble carriers for said poorly water-soluble bio-active agent, said carriers being selected from the group consisting of polyols, and (d) water. Such coacervate compositions may be dried into solid dosage forms from which rapid release of the bio-active agent can be obtained.
IPC 8 full level
A61K 9/10 (2006.01); A61K 9/16 (2006.01); A61K 47/10 (2006.01); A61K 47/26 (2006.01); A61K 47/44 (2006.01); C14B 1/04 (2006.01)
CPC (source: EP)
A61K 9/1641 (2013.01); A61K 9/1694 (2013.01); C14B 1/04 (2013.01); C14B 1/26 (2013.01); A61K 9/19 (2013.01); C14B 2700/016 (2013.01)
Citation (search report)
- [XP] WO 2010081815 A1 20100722 - UNIV GENT [BE], et al
- [A] WO 0064575 A1 20001102 - EURAND INT [IT], et al
- [A] US 4794000 A 19881227 - ECANOW BERNARD [US]
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
EP 2407156 A2 20120118; EP 2407156 A3 20120711; GB 201011821 D0 20100901
DOCDB simple family (application)
EP 11174030 A 20110714; GB 201011821 A 20100714