EP 2419110 A1 20120222 - METHODS OF TREATING CANCERS WITH HER3 ANTISENSE OLIGONUCLEOTIDES
Title (en)
METHODS OF TREATING CANCERS WITH HER3 ANTISENSE OLIGONUCLEOTIDES
Title (de)
VERFAHREN ZUR BEHANDLUNG VON KREBS MIT HER3-ANTISENSE-OLIGONUKLEOTIDEN
Title (fr)
PROCÉDÉS DE TRAITEMENT DE CANCERS AVEC DES OLIGONUCLÉOTIDES ANTISENS DE HER3
Publication
Application
Priority
- US 2010031005 W 20100414
- US 16909309 P 20090414
Abstract (en)
[origin: WO2010120861A1] One aspect of the invention provides methods for treating cancers which are resistant to treatment with a protein tyrosine kinase inhibitor by co-treatment with the protein tyrosine kinase inhibitor and one or more antisense oligomers that reduce the expression of HER3 and/or HER2 and/or EGFR. Another aspect of the invention provides methods for treating cancers by co-treatment with an inhibitor of HER2 and one or more antisense oligomers that reduce the expression of HER3.
IPC 8 full level
A61K 31/70 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01)
CPC (source: EP KR US)
A61K 31/70 (2013.01 - KR); A61K 48/00 (2013.01 - KR); A61P 35/00 (2017.12 - EP); A61P 35/02 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 487/04 (2013.01 - EP US); C07D 519/00 (2013.01 - EP US); C07H 21/04 (2013.01 - KR); C12N 15/1137 (2013.01 - EP US); C12N 2310/11 (2013.01 - EP US); C12N 2310/315 (2013.01 - EP US); C12N 2310/3231 (2013.01 - EP US); C12N 2310/3341 (2013.01 - EP US); C12N 2310/341 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
DOCDB simple family (publication)
WO 2010120861 A1 20101021; AR 076053 A1 20110518; CA 2758005 A1 20101021; CN 102395374 A 20120328; EA 201171244 A1 20120530; EP 2419110 A1 20120222; EP 2419110 A4 20130807; IL 215683 A0 20120131; JP 2012524096 A 20121011; KR 20140014367 A 20140206; TW 201036619 A 20101016; US 2012076781 A1 20120329
DOCDB simple family (application)
US 2010031005 W 20100414; AR P100101205 A 20100408; CA 2758005 A 20100414; CN 201080016819 A 20100414; EA 201171244 A 20100414; EP 10765073 A 20100414; IL 21568311 A 20111010; JP 2012506153 A 20100414; KR 20117027050 A 20100414; TW 99111589 A 20100414; US 201013264265 A 20100414