Global Patent Index - EP 2421542 A4

EP 2421542 A4 20130424 - FOAMYVIRUS VECTORS AND METHODS OF USE

Title (en)

FOAMYVIRUS VECTORS AND METHODS OF USE

Title (de)

FOAMYVIRUSVEKTOREN UND VERWENDUNGSVERFAHREN

Title (fr)

VECTEURS DE VIRUS SPUMEUX ET LEURS PROCÉDÉS D'UTILISATION

Publication

EP 2421542 A4 20130424 (EN)

Application

EP 10756923 A 20100326

Priority

  • US 2010028854 W 20100326
  • US 16367309 P 20090326

Abstract (en)

[origin: WO2010111608A1] The disclosure of the present application provides foamyvirus vectors, as well as methods and kits involving the same. In at least one embodiment, a plurality of recombinant vectors comprises an expression sequence encoding at least one component of a foamyvirus particle, wherein at least one codon of the expression sequence is optimized for expression in homo sapiens.

IPC 8 full level

C12N 15/867 (2006.01); A61K 48/00 (2006.01)

CPC (source: EP)

A61K 31/7088 (2013.01); C12N 15/86 (2013.01); C12N 2740/17043 (2013.01); C12N 2740/17052 (2013.01)

Citation (search report)

  • [AP] EP 2138584 A1 20091230 - VECTORIA FORSCHUNGSFOERDERUNGS [DE]
  • [XYI] RETHWILM AXEL: "Foamy virus vectors: an awaited alternative to gammaretro- and lentiviral vectors", CURRENT GENE THERAPY, vol. 7, no. 4, 1 August 2007 (2007-08-01), pages 261 - 271, XP009161696, ISSN: 1566-5232
  • [XI] JOSEPHSON NEIL C ET AL: "Transduction of long-term and mobilized peripheral blood-derived NOD/SCID repopulating cells by foamy virus vectors.", HUMAN GENE THERAPY, vol. 15, no. 1, January 2004 (2004-01-01), pages 87 - 92, XP002693163, ISSN: 1043-0342
  • [XI] TROBRIDGE GRANT ET AL: "Improved foamy virus vectors with minimal viral sequences.", MOLECULAR THERAPY, vol. 6055055113, no. 3, September 2002 (2002-09-01), pages 321 - 328, XP055055113, ISSN: 1525-0016
  • [Y] FANG Y ET AL: "Higher-Order Oligomerization Targets Plasma Membrane Proteins and HIV Gag to Exosomes", PLOS BIOLOGY, vol. 5, no. 6, 1 June 2007 (2007-06-01), pages 1267 - 1283, XP008136116, ISSN: 1544-9173, DOI: 10.1371/JOURNAL.PBIO.0050158 & DATABASE EMBL [online] 24 June 2007 (2007-06-24), WU AND GOULD: "Synthetic construct SFV-gag protein (gag) gene, complete cds.", XP002693164, Database accession no. DQ866825
  • [A] Y. LI ET AL: "Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg-/- mice in vivo", BLOOD, vol. 113, no. 10, 5 March 2009 (2009-03-05), pages 2342 - 2351, XP055055184, ISSN: 0006-4971, DOI: 10.1182/blood-2008-07-168138
  • See references of WO 2010111608A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

DOCDB simple family (publication)

WO 2010111608 A1 20100930; EP 2421542 A1 20120229; EP 2421542 A4 20130424

DOCDB simple family (application)

US 2010028854 W 20100326; EP 10756923 A 20100326