EP 2438062 B1 20150729 - PROCESS FOR THE PREPARATION OF AMORPHOUS RALTEGRAVIR POTASSIUM
Title (en)
PROCESS FOR THE PREPARATION OF AMORPHOUS RALTEGRAVIR POTASSIUM
Title (de)
VERFAHREN ZUR HERSTELLUNG VON AMORPHEM RALTEGRAVIR-KALIUM
Title (fr)
PROCÉDÉ DE PRÉPARATION DE POTASSIUM DE RALTÉGRAVIR AMORPHE
Publication
Application
Priority
IN 2009000317 W 20090602
Abstract (en)
[origin: WO2010140156A2] The present invention provides novel polymorphs of raltegravir potassium, processes for their preparation and pharmaceutical compositions comprising them. Thus for example, raltegravir potassium was added to water and stirred for 15 minutes, the solution was filtered on hiflo bed and the bed washed with water, the resulting solution was subjected to freeze drying at -180 deg C for 13 hours to give raltegravir potassium amorphous form.
IPC 8 full level
C07D 413/12 (2006.01)
CPC (source: EP US)
C07D 413/12 (2013.01 - EP US); C07B 2200/13 (2013.01 - US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2010140156 A2 20101209; WO 2010140156 A3 20120927; EP 2438062 A2 20120411; EP 2438062 A4 20130731; EP 2438062 B1 20150729; ES 2549387 T3 20151027; US 2012178930 A1 20120712; US 8742105 B2 20140603
DOCDB simple family (application)
IN 2009000317 W 20090602; EP 09845466 A 20090602; ES 09845466 T 20090602; US 200913375575 A 20090602