Global Patent Index - EP 2445484 A1

EP 2445484 A1 20120502 - APREPITANT IN THE FORM OF A SOLID SOLUTION

Title (en)

APREPITANT IN THE FORM OF A SOLID SOLUTION

Title (de)

APREPITANT IN FORM EINER FESTEN LÖSUNG

Title (fr)

APRÉPITANT SOUS FORME DE SOLUTION SOLIDE

Publication

EP 2445484 A1 20120502 (DE)

Application

EP 09776827 A 20090624

Priority

EP 2009004558 W 20090624

Abstract (en)

[origin: WO2010149183A1] The invention relates to a method for producing an intermediate containing aprepitant and matrix material, wherein aprepitant is present in the form of a solid solution.

IPC 8 full level

A61K 9/16 (2006.01); A61K 9/20 (2006.01); A61K 31/5377 (2006.01)

CPC (source: EP)

A61K 9/1635 (2013.01); A61K 9/2027 (2013.01); A61K 9/2077 (2013.01); A61K 31/5377 (2013.01)

Citation (search report)

See references of WO 2010149183A1

Citation (examination)

  • WO 2008110534 A1 20080918 - SANDOZ AG [CH], et al
  • LEUNER C ET AL: "Improving drug solubility for oral delivery using solid dispersions", EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, ELSEVIER SCIENCE PUBLISHERS B.V., AMSTERDAM, NL, vol. 50, no. 1, 3 July 2000 (2000-07-03), pages 47 - 60, XP004257179, ISSN: 0939-6411, DOI: 10.1016/S0939-6411(00)00076-X

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2010149183 A1 20101229; EP 2445484 A1 20120502

DOCDB simple family (application)

EP 2009004558 W 20090624; EP 09776827 A 20090624