EP 2446043 A4 20130213 - YEAST ORGANISMS FOR THE PRODUCTION OF ISOBUTANOL
Title (en)
YEAST ORGANISMS FOR THE PRODUCTION OF ISOBUTANOL
Title (de)
HEFEORGANISMEN ZUR HERSTELLUNG VON ISOBUTANOL
Title (fr)
ORGANISMES DE LEVURE POUR LA PRODUCTION D'ISOBUTANOL
Publication
Application
Priority
- US 2010039447 W 20100622
- US 21917309 P 20090622
- US 69664510 A 20100129
Abstract (en)
[origin: WO2010151525A1] The present invention provides recombinant microorganisms comprising an isobutanol producing metabolic pathway and methods of using said recombinant microorganisms to produce isobutanol. In various aspects of the invention, the recombinant microorganisms may comprise a modification resulting in the reduction of pyruvate decarboxylase and/or glycerol-3-phosphate dehydrogenase activity. In various embodiments described herein, the recombinant microorganisms may be microorganisms of the Saccharomyces clade, Crabtree-negative yeast microorganisms, Crabtree-positive yeast microorganisms, post-WGD (whole genome duplication) yeast microorganisms, pre-WGD (whole genome duplication) yeast microorganisms, and non-fermenting yeast microorganisms.
IPC 8 full level
CPC (source: EP)
C12N 1/16 (2013.01); C12P 7/16 (2013.01); Y02E 50/10 (2013.01)
Citation (search report)
- [Y] US 2007092957 A1 20070426 - DONALDSON GAIL K [US], et al
- [Y] LEE S K ET AL: "Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels", CURRENT OPINION IN BIOTECHNOLOGY, LONDON, GB, vol. 19, no. 6, 1 December 2008 (2008-12-01), pages 556 - 563, XP025745480, ISSN: 0958-1669, [retrieved on 20081110], DOI: 10.1016/J.COPBIO.2008.10.014
- [Y] ZHONG-PENG GUO ET AL: "Interruption of glycerol pathway in industrial alcoholic yeasts to improve the ethanol production", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER, BERLIN, DE, vol. 82, no. 2, 19 November 2008 (2008-11-19), pages 287 - 292, XP019705425, ISSN: 1432-0614
- [A] M. R. CONNOR ET AL: "Engineering of an Escherichia coli Strain for the Production of 3-Methyl-1-Butanol", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 74, no. 18, 1 August 2008 (2008-08-01), pages 5769 - 5775, XP055047091, ISSN: 0099-2240, DOI: 10.1128/AEM.00468-08
- [AD] ATSUMI SHOTA ET AL: "Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels", NATURE: INTERNATIONAL WEEKLY JOURNAL OF SCIENCE, NATURE PUBLISHING GROUP, UNITED KINGDOM, vol. 451, no. 7174, 1 January 2008 (2008-01-01), pages 86 - 90, XP002491157, ISSN: 0028-0836, DOI: 10.1038/NATURE06450
- [A] VAN VLEET J ET AL: "Yeast metabolic engineering for hemicellulosic ethanol production", CURRENT OPINION IN BIOTECHNOLOGY, LONDON, GB, vol. 20, no. 3, 1 June 2009 (2009-06-01), pages 300 - 306, XP026283532, ISSN: 0958-1669, [retrieved on 20090621], DOI: 10.1016/J.COPBIO.2009.06.001
- [A] BENGTSSON O ET AL: "Xylose reductase from Pichia stipitis with altered coenzyme preference improves ethanolic xylose fermentation by recombinant Saccharomyces cerevisiae", BIOTECHNOLOGY FOR BIOFUELS, BIOMED CENTRAL LTD, GB, vol. 2, 5 May 2009 (2009-05-05), pages 1 - 10, XP002612933, ISSN: 1754-6834, DOI: 10.1186/1754-6834-2-9
- See references of WO 2010151525A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
DOCDB simple family (publication)
WO 2010151525 A1 20101229; EP 2446043 A1 20120502; EP 2446043 A4 20130213
DOCDB simple family (application)
US 2010039447 W 20100622; EP 10792562 A 20100622