EP 2451471 A1 20120516 - SLOW-ACTING INSULIN PREPARATIONS
Title (en)
SLOW-ACTING INSULIN PREPARATIONS
Title (de)
LANGSAMWIRKENDE INSULINZUBEREITUNGEN
Title (fr)
PRÉPARATIONS D'INSULINE À EFFET RETARD
Publication
Application
Priority
- EP 2010059438 W 20100702
- DE 102009031750 A 20090706
- DE 102010013133 A 20100327
Abstract (en)
[origin: WO2011003823A1] The invention relates to aqueous pharmaceutical formulations having an insulin analog, said formulations comprising 0.001 to 0.2 mg/ml of zinc, 0.1 to 5.0 mg/ml of a preservative, and 5.0 to 100 mg/ml of an isotonic agent, and the pH value of which is 5 or less. The invention further relates to the production thereof, the use thereof for treating diabetes mellitus, and a medication for treating diabetes mellitus.
IPC 8 full level
A61K 38/28 (2006.01); A61P 3/10 (2006.01)
CPC (source: EP US)
A61K 9/0019 (2013.01 - EP US); A61K 47/10 (2013.01 - EP US); A61P 3/10 (2017.12 - EP); A61P 5/50 (2017.12 - EP); C07K 14/62 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US)
Citation (search report)
See references of WO 2011003823A1
Citation (examination)
- US 6100376 A 20000808 - DOERSCHUG MICHAEL [DE]
- WO 2007081824 A2 20070719 - UNIV CASE WESTERN RESERVE [US], et al
- WO 8910937 A1 19891116 - NOVO NORDISK AS [DK]
- MARKUSSEN J ET AL: "SOLUBLE, PROLONGED-ACTING INSULIN DERIVATIVES. I. DEGREE OF PROTRACTION AND CRYSTALLIZABILITY OF INSULINS SUBSTITUTED IN THE TERMINI OF THE B-CHAIN", PROTEIN ENGINEERING, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 1, no. 3, 1 June 1987 (1987-06-01), pages 205 - 213, XP000000187, ISSN: 0269-2139
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
DOCDB simple family (publication)
WO 2011003823 A1 20110113; AR 077455 A1 20110831; EP 2451471 A1 20120516; JP 2012532179 A 20121213; JP 5675799 B2 20150225; TW 201113032 A 20110416; US 2012232002 A1 20120913; UY 32765 A 20110131
DOCDB simple family (application)
EP 2010059438 W 20100702; AR P100102419 A 20100706; EP 10726993 A 20100702; JP 2012518920 A 20100702; TW 99121772 A 20100702; US 201013382772 A 20100702; UY 32765 A 20100705