Global Patent Index - EP 2456423 A2

EP 2456423 A2 20120530 - TREATMENT OF HYPERPROLIFERATIVE CONDITIONS

Title (en)

TREATMENT OF HYPERPROLIFERATIVE CONDITIONS

Title (de)

BEHANDLUNG VON HYPERPROLIFERATIVEN ERKRANKUNGEN

Title (fr)

TRAITEMENT DE TROUBLES HYPERPROLIFÉRATIFS

Publication

EP 2456423 A2 20120530 (EN)

Application

EP 10734023 A 20100708

Priority

  • DK PA200900874 A 20090717
  • DK 2010050179 W 20100708

Abstract (en)

[origin: WO2011006504A2] The present invention relates to stable pharmaceutical formulations comprising a solubilized lipophilic anthracycline and the uses thereof in the treatment of clinical conditions, wherein hyperproliferation, such as epithelial hyperproliferation, is a primary factor of the pathogenesis. The pharmaceutical compositions comprises i) a lipophilic anthracycline; ii) one or more oil phase carriers; iii) one or more pharmaceutical acceptable solubilizers; iv) one or more co-surfactants; and the composition further comprises an aqueous phase comprising at least one buffering system having a pH from about pH 2.2 to about pH 6, wherein the water content of the pharmaceutical composition is less than 30%.

IPC 8 full level

A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 9/107 (2006.01); A61K 31/65 (2006.01); A61K 47/10 (2006.01); A61K 47/14 (2006.01)

CPC (source: EP)

A61K 9/0014 (2013.01); A61K 9/0034 (2013.01); A61K 9/06 (2013.01); A61K 9/107 (2013.01); A61K 31/65 (2013.01); A61K 47/10 (2013.01); A61K 47/14 (2013.01)

Citation (search report)

See references of WO 2011006504A2

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

DOCDB simple family (publication)

WO 2011006504 A2 20110120; WO 2011006504 A3 20111020; EP 2456423 A2 20120530

DOCDB simple family (application)

DK 2010050179 W 20100708; EP 10734023 A 20100708