EP 2465864 A3 20121003 - Peptide vaccines for cancers expressing tumor-associated antigens
Title (en)
Peptide vaccines for cancers expressing tumor-associated antigens
Title (de)
Peptidvakzine für tumorassoziierte Antigene exprimierenden Krebs
Title (fr)
Vaccins de peptide pour cancers exprimant des antigènes associés aux tumeurs
Publication
Application
Priority
- EP 08710443 A 20080221
- US 90294907 P 20070221
Abstract (en)
[origin: WO2008102557A1] The present invention provides peptides having an amino acid sequence as set forth in SEQ ID NO: SEQ ID NO: 19, 22, 30, 34, 344, 358, 41, 44, 46, 48, 78, 376, 379, 80, 100, 101, 110, 111, 387, 112, 394, 114, 116, 117, 121, 395, 133, 135, 137, 426, 174, 178, 186, 194, 196, 202, 210, 213, 214, 217, 223, 227, 228, 233, 254, 271, 272 or 288, as well as peptides having the above-mentioned amino acid sequences in which 1, 2, or several (e.g., up to 5) amino acids are substituted, deleted, or added, provided the peptides possess cytotoxic T cell inducibility. The present invention also provides drugs for treating or preventing a disease associated with over-expression of the CDH3, EPHA4, ECT2, HIG2, INHBB, KIF20A, KNTC2, TTK and/or URLC10, e.g. cancers containing as an active ingredient one or more of these peptides. The peptides of the present invention find further utility as vaccines.
IPC 8 full level
C07K 14/47 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01); C07K 14/745 (2006.01); C12N 5/10 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01)
CPC (source: EP KR US)
A61K 9/127 (2013.01 - KR); A61K 38/08 (2013.01 - KR); A61K 39/0011 (2013.01 - EP KR US); A61K 39/001122 (2018.08 - EP US); A61K 39/4611 (2023.05 - EP US); A61K 39/464402 (2023.05 - EP US); A61K 39/464422 (2023.05 - EP US); A61K 39/464434 (2023.05 - EP US); A61K 39/464462 (2023.05 - EP US); A61K 39/464466 (2023.05 - EP US); A61P 35/00 (2018.01 - EP KR); A61P 37/04 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07K 7/06 (2013.01 - KR); C07K 14/47 (2013.01 - EP); C07K 14/4748 (2013.01 - EP); C12N 5/0634 (2013.01 - EP KR US); C12N 5/0638 (2013.01 - EP KR US); G01N 33/505 (2013.01 - KR); A61K 2039/55555 (2013.01 - EP KR); C12N 2501/998 (2013.01 - KR); C12N 2510/00 (2013.01 - KR)
Citation (search report)
- [X] US 2006093617 A1 20060504 - BUYSE MARIE-ANGE [BE], et al
- [A] SUDA TAKAKO ET AL: "Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray", CANCER SCIENCE,, vol. 97, no. 5, 1 May 2006 (2006-05-01), pages 411 - 419, XP002542757
- [A] HARADA M ET AL: "Kinesin superfamily protein-derived peptides with the ability to induce glioma-reactive cytotoxic T lymphocytes in human leukocyte antigen-A24+ glioma patients", ONCOLOGY REPORTS, NATIONAL HELLENIC RESEARCH FOUNDATION, ATHENS, GR, vol. 17, no. 3, 1 January 2007 (2007-01-01), pages 629 - 636, XP003019917, ISSN: 1021-335X
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
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DOCDB simple family (application)
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