EP 2465950 A2 20120620 - K-RAS MUTATIONS AND ANTI-EGFR ANTIBODY THERAPY

Title (en)

K-RAS MUTATIONS AND ANTI-EGFR ANTIBODY THERAPY

Title (de)

K-RAS-Mutationen und Anti-EGFR-Antikörpertherapie

Title (fr)

Mutations de K-RAS et traitement avec des anticorps anti-EGFR

Publication

EP 2465950 A2 20120620 (EN)

Application

EP 12154109 A 20080311

Priority

EP 08742061 A 20080311
US 90694307 P 20070313

Abstract (en)

The present application relates to K-ras mutations, to polynucleotides encoding mutant K-ras polypeptides, and to methods of identifying K-ras mutations. The present application also relates to methods of diagnosing cancer; and methods and kits for predicting the usefulness of anti-EGFr specific binding agents in the treatment of tumors.

IPC 8 full level

C12Q 1/68 (2006.01)

CPC (source: EP US)

C12Q 1/6886 (2013.01 - EP US); C12Q 2600/118 (2013.01 - EP US)

Citation (applicant)

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Designated contracting state (EPC)

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Designated extension state (EPC)

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DOCDB simple family (application)

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