EP 2470651 A1 20120704 - LUNG AND ESOPHAGEAL CANCER RELATED GENE ADAMTS18
Title (en)
LUNG AND ESOPHAGEAL CANCER RELATED GENE ADAMTS18
Title (de)
MIT LUNGEN- UND SPEISERÖHRENKREBS ASSOZIIERTES GEN ADAMTS18
Title (fr)
GÈNE ADAMTS18 LIÉ AU CANCER DU POUMON ET AU CANCER DE L' SOPHAGE
Publication
Application
Priority
- US 27503909 P 20090824
- JP 2010005185 W 20100823
Abstract (en)
[origin: WO2011024433A1] The present invention provides methods for detecting and diagnosing cancer, such methods involving the determination of the expression level of the ADAMTS18 gene. This gene was discovered to discriminate cancer cells from normal cells. Furthermore, the present invention provides methods of screening for therapeutic agents useful in the treatment of cancer and methods for treating cancer. Moreover, the present invention provides double-stranded molecules targeting the ADAMTS18, all of which are suggested to be useful in the treatment of cancer.
IPC 8 full level
C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61K 45/00 (2006.01); C12Q 1/68 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); C12Q 1/6886 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01)
Citation (search report)
See references of WO 2011024433A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
DOCDB simple family (publication)
WO 2011024433 A1 20110303; CN 102597235 A 20120718; EP 2470651 A1 20120704; JP 2013502203 A 20130124
DOCDB simple family (application)
JP 2010005185 W 20100823; CN 201080048031 A 20100823; EP 10811492 A 20100823; JP 2012510050 A 20100823