EP 2473160 A1 20120711 - DELIVERY OF THERAPEUTIC AGENTS USING OLIGONUCLEOTIDE-MODIFIED NANOPARTICLES AS CARRIERS
Title (en)
DELIVERY OF THERAPEUTIC AGENTS USING OLIGONUCLEOTIDE-MODIFIED NANOPARTICLES AS CARRIERS
Title (de)
VERABREICHUNG THERAPEUTISCHER MITTEL MIT OLIGONUKLEOTIDMODIFIZIERTEN NANOPARTIKELN ALS TRÄGERN
Title (fr)
DISTRIBUTION D'AGENTS THÉRAPEUTIQUES À L'AIDE DE NANOPARTICULES MODIFIÉES PAR OLIGONUCLÉOTIDES EN TANT QUE VÉHICULES
Publication
Application
Priority
- US 31411410 P 20100315
- US 23893009 P 20090901
- US 2010047594 W 20100901
Abstract (en)
[origin: WO2011028850A1] Disclosed are drug delivery compositions comprising an oligonucleotide-modified nanoparticle and a therapeutic agent. Specifically, disclosed are compositions comprising a number of oligonucleotide molecules in a ratio to therapeutic agent molecules to allow a sufficient transportation of the therapeutic agent molecules into a cell. The therapeutic agents include both hydrophobic and hydrophilic. Different attachments of therapeutic agents in a composition are also described.
IPC 8 full level
A61K 9/16 (2006.01); A61K 47/48 (2006.01)
CPC (source: EP US)
A61K 31/337 (2013.01 - US); A61K 47/26 (2013.01 - US); A61K 47/6923 (2017.07 - EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
DOCDB simple family (publication)
WO 2011028850 A1 20110310; AU 2010289483 A1 20120329; CA 2772660 A1 20110310; CN 102625697 A 20120801; EP 2473160 A1 20120711; EP 2473160 A4 20150603; JP 2013503885 A 20130204; JP 2015017124 A 20150129; US 2012283316 A1 20121108; US 2014005258 A1 20140102
DOCDB simple family (application)
US 2010047594 W 20100901; AU 2010289483 A 20100901; CA 2772660 A 20100901; CN 201080048673 A 20100901; EP 10814463 A 20100901; JP 2012528023 A 20100901; JP 2014211425 A 20141016; US 201013393463 A 20100901; US 201314020081 A 20130906