EP 2480664 A1 20120801 - AMIDASE AND USE THEREOF FOR PRODUCING 3-AMINO CARBOXYLIC ACID ESTERS
Title (en)
AMIDASE AND USE THEREOF FOR PRODUCING 3-AMINO CARBOXYLIC ACID ESTERS
Title (de)
AMIDASE UND IHRE VERWENDUNG ZUR HERSTELLUNG VON 3-AMINOCARBONSÄUREESTERN
Title (fr)
AMIDASE ET SON UTILISATION POUR LA PRODUCTION D'ESTERS D'ACIDE 3-AMINOCARBOXILIQUE
Publication
Application
Priority
- EP 09171414 A 20090925
- EP 2010064098 W 20100924
- EP 10757596 A 20100924
Abstract (en)
[origin: WO2011036233A1] The invention relates to a method for producing optically active 3-amino carboxylic acid ester compounds of general formula I, and the ammonium salts thereof, where R1 is alkyl, alkoxyalkyl, alkenyl, cycloalkyl, heterocycloalkyl, aryl, or hetaryl, and R2 is alkyl, cycloalkyl or aryl, wherein an enantiomer mixture of a simple N-acylized 3-amino carboxylic acid ester of general formula (1.b), where R1 and R2 are as defined above and R3 is hydrogen, alkyl, cycloalkyl, or aryl, is subjected to an enantioselective deacylation by adding a polypeptide according to claim 1.
IPC 8 full level
C12N 9/80 (2006.01); C12P 13/04 (2006.01); C12P 41/00 (2006.01)
CPC (source: EP US)
C12N 9/80 (2013.01 - EP US); C12P 13/001 (2013.01 - US); C12P 13/04 (2013.01 - EP US); C12P 41/007 (2013.01 - EP US)
Citation (search report)
See references of WO 2011036233A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
DOCDB simple family (publication)
WO 2011036233 A1 20110331; CN 102549151 A 20120704; EP 2480664 A1 20120801; JP 2013505710 A 20130221; US 2013005002 A1 20130103; US 2013337512 A1 20131219; US 8932837 B2 20150113
DOCDB simple family (application)
EP 2010064098 W 20100924; CN 201080042450 A 20100924; EP 10757596 A 20100924; JP 2012530267 A 20100924; US 201013497985 A 20100924; US 201313942184 A 20130715