EP 2481756 A3 20120808 - Compositions and methods for diagnosing and treating cancer
Title (en)
Compositions and methods for diagnosing and treating cancer
Title (de)
Zusammensetzungen und Verfahren zur Diagnose und Behandlung von Krebs
Title (fr)
Compositions et procédés pour le diagnostic et le traitement du cancer
Publication
Application
Priority
- EP 06844236 A 20061031
- US 73146805 P 20051031
- US 81296606 P 20060613
Abstract (en)
[origin: WO2007053577A2] An isolated antibody that specifically binds to an extracellular domain of two or more human FZD receptors and inhibits growth of tumor cells is described. Also described is a method of treating cancer comprising administering an antibody of the present disclosure in an amount effective to inhibit tumor cell growth.
IPC 8 full level
C07K 16/28 (2006.01); A61K 38/17 (2006.01); A61K 45/06 (2006.01); C07K 16/30 (2006.01); C07K 16/46 (2006.01)
CPC (source: EP US)
A61K 45/06 (2013.01 - EP US); A61P 1/04 (2017.12 - EP); A61P 1/18 (2017.12 - EP); A61P 11/00 (2017.12 - EP); A61P 13/08 (2017.12 - EP); A61P 15/00 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 35/02 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07K 16/2896 (2013.01 - EP US); C07K 16/30 (2013.01 - EP US); C07K 16/468 (2013.01 - EP US); A61K 2039/505 (2013.01 - EP US); C07K 2317/73 (2013.01 - EP US); C07K 2317/732 (2013.01 - EP US); C07K 2317/734 (2013.01 - EP US); C07K 2317/76 (2013.01 - EP US)
Citation (search report)
- [Y] WO 2004032838 A2 20040422 - UNIV CALIFORNIA [US], et al
- [Y] WO 2004042028 A2 20040521 - UNIV CALIFORNIA [US], et al
- [A] SEN M ET AL: "BLOCKADE OF WNT-5A/FRIZZLED 5 SIGNALING INHIBITS RHEUMATOID SYNOVIOCYTE ACTIVATION", ARTHRITIS & RHEUMATISM, JOHN WILEY & SONS, INC, US, vol. 44, no. 4, 1 April 2001 (2001-04-01), pages 772 - 781, XP009012409, ISSN: 0004-3591, DOI: 10.1002/1529-0131(200104)44:4<772::AID-ANR133>3.0.CO;2-L
- [A] R. FREDRIKSSON ET AL: "The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints", MOLECULAR PHARMACOLOGY, vol. 63, no. 6, 1 June 2003 (2003-06-01), pages 1256 - 1272, XP055029878, ISSN: 0026-895X, DOI: 10.1124/mol.63.6.1256
- [A] NAGAYAMA SATOSHI ET AL: "Therapeutic potential of antibodies against FZD10, a cell-surface protein, for synovial sarcomas", ONCOGENE, NATURE PUBLISHING GROUP, GB, vol. 24, no. 41, 15 September 2005 (2005-09-15), pages 6201 - 6212, XP002354477, ISSN: 0950-9232, DOI: 10.1038/SJ.ONC.1208780
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2007053577 A2 20070510; WO 2007053577 A3 20071206; AU 2006308870 A1 20070510; AU 2006308870 B2 20120816; AU 2006344359 A1 20071213; AU 2006344359 B2 20130815; CA 2628116 A1 20071213; CA 2628221 A1 20070510; CN 102827287 A 20121219; CN 102827287 B 20150812; DK 1978993 T3 20170320; DK 2481756 T3 20171009; DK 2500360 T3 20151026; EP 1961065 A2 20080827; EP 1961065 A4 20091111; EP 1978993 A2 20081015; EP 1978993 A4 20091118; EP 1978993 B1 20161214; EP 2479192 A1 20120725; EP 2481756 A2 20120801; EP 2481756 A3 20120808; EP 2481756 B1 20170802; EP 2500360 A2 20120919; EP 2500360 A3 20121212; EP 2500360 B1 20150805; EP 2511298 A2 20121017; EP 2511298 A3 20130213; EP 2511298 B1 20190116; ES 2547421 T3 20151006; ES 2618785 T3 20170622; ES 2641087 T3 20171107; HK 1175792 A1 20130712; HK 1179275 A1 20130927; HR P20151172 T1 20151204; HU E025908 T2 20160428; HU E031122 T2 20170728; JP 2009513708 A 20090402; JP 2009515513 A 20090416; JP 2013039127 A 20130228; JP 2013241409 A 20131205; JP 5368798 B2 20131218; JP 5837466 B2 20151224; ME 02226 B 20160220; PL 1978993 T3 20170731; PL 2481756 T3 20180228; PL 2500360 T3 20160129; PT 1978993 T 20170317; PT 2500360 E 20151015; RS 54215 B1 20151231; SI 2500360 T1 20151130; US 2007116701 A1 20070524; US 2018222997 A1 20180809; US 9850311 B2 20171226; WO 2007133250 A2 20071122; WO 2007133250 A3 20090326; WO 2007142711 A2 20071213; WO 2007142711 A3 20081218
DOCDB simple family (application)
US 2006042375 W 20061031; AU 2006308870 A 20061031; AU 2006344359 A 20061031; CA 2628116 A 20061031; CA 2628221 A 20061031; CN 201210285145 A 20061031; DK 07752161 T 20061031; DK 12154780 T 20061031; DK 12156146 T 20061031; EP 06844236 A 20061031; EP 07752161 A 20061031; EP 12154780 A 20061031; EP 12154787 A 20061031; EP 12156146 A 20061031; EP 12156151 A 20061031; ES 07752161 T 20061031; ES 12154780 T 20061031; ES 12156146 T 20061031; HK 13103296 A 20130318; HK 13106435 A 20130531; HR P20151172 T 20151103; HU E07752161 A 20061031; HU E12156146 A 20061031; JP 2008538957 A 20061031; JP 2008539171 A 20061031; JP 2012183807 A 20120823; JP 2013112663 A 20130529; ME P16415 A 20061031; PL 07752161 T 20061031; PL 12154780 T 20061031; PL 12156146 T 20061031; PT 07752161 T 20061031; PT 12156146 T 20061031; RS P20150577 A 20061031; SI 200631984 T 20061031; US 2006042374 W 20061031; US 2007005443 W 20061031; US 201715817998 A 20171120; US 58999306 A 20061031