Global Patent Index - EP 2491932 A2

EP 2491932 A2 20120829 - Use of biomarkers for monitoring the course of treatment of a pulmonary disease upon treatment with treprostinil

Title (en)

Use of biomarkers for monitoring the course of treatment of a pulmonary disease upon treatment with treprostinil

Title (de)

Verwendung von Biomarkern zur Überwachung des Verlaufs der Behandlung einer Lungenerkrankung bei Behandlung mit Treprostinil

Title (fr)

Utilisation de biomarqueurs pour surveiller le courant de traitement d'une maladie pulmonaire après traitement avec tréprostinil

Publication

EP 2491932 A2 20120829 (EN)

Application

EP 12162497 A 20080208

Priority

  • EP 08729432 A 20080208
  • US 90032007 P 20070209
  • US 94021807 P 20070525

Abstract (en)

The present invention describes methods for using Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of interstitial lung disease or asthma, or a condition, such as pulmonary fibrosis, associated with interstitial lung disease or a condition associated with asthma. The invention also relates to kits for treatment and/or prevention of such condition that include an effective amount of Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof.

IPC 8 full level

A61K 31/557 (2006.01); A61P 11/00 (2006.01); A61P 11/06 (2006.01); G01N 33/50 (2006.01)

CPC (source: EP KR US)

A61K 9/08 (2013.01 - KR); A61K 31/192 (2013.01 - KR US); A61K 31/557 (2013.01 - EP US); A61K 31/5575 (2013.01 - KR US); A61P 1/04 (2018.01 - EP KR); A61P 9/08 (2018.01 - EP KR); A61P 9/10 (2018.01 - EP KR); A61P 9/12 (2018.01 - EP KR); A61P 11/00 (2018.01 - EP); A61P 11/06 (2018.01 - EP KR); A61P 11/16 (2018.01 - EP KR); A61P 19/04 (2018.01 - EP KR); A61P 21/02 (2018.01 - EP KR); A61P 25/04 (2018.01 - EP KR); A61P 29/00 (2018.01 - EP KR); G01N 33/5008 (2013.01 - EP US); G01N 33/502 (2013.01 - US); G01N 33/5041 (2013.01 - EP KR US)

Citation (applicant)

  • US 6521212 B1 20030218 - CLOUTIER GILLES [US], et al
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  • US 4306075 A 19811215 - ARISTOFF PAUL A
  • US 6528688 B2 20030304 - MORIARTY ROBERT M [US], et al
  • US 6441245 B1 20020827 - MORIARTY ROBERT M [US], et al
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  • IDZKO M; HAMMAD H; VAN NIMWEGEN M ET AL.: "Inhaled iloprost suppresses the cardinal features of asthma via inhibition of airway dendritic cell function", J CLIN INVEST, vol. 117, 2007, pages 464 - 472
  • JAFFAR Z; WAN K-S; ROBERTS K: "A key role for prostaglandin 12 in limiting lung mucosal Th2, but not Thl, responses to inhaled allergen", J IMMUNOL, vol. 169, 2002, pages 5997 - 6004
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Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2008098196 A1 20080814; CA 2678258 A1 20080814; CN 101678033 A 20100324; CN 102648916 A 20120829; EP 2120961 A1 20091125; EP 2491932 A2 20120829; EP 2491932 A3 20121212; JP 2010518122 A 20100527; JP 2013189459 A 20130926; KR 20090117781 A 20091112; US 2008280986 A1 20081113; US 2012129941 A1 20120524; US 2013096200 A1 20130418; US 2014018431 A1 20140116

DOCDB simple family (application)

US 2008053467 W 20080208; CA 2678258 A 20080208; CN 200880004381 A 20080208; CN 201210059997 A 20080208; EP 08729432 A 20080208; EP 12162497 A 20080208; JP 2009549268 A 20080208; JP 2013116923 A 20130603; KR 20097018462 A 20080208; US 201213360961 A 20120130; US 201213709270 A 20121210; US 201314030500 A 20130918; US 2847108 A 20080208