Global Patent Index - EP 2493299 A4

EP 2493299 A4 20130417 - TERTIARY AMIDE OREXIN RECEPTOR ANTAGONISTS

Title (en)

TERTIARY AMIDE OREXIN RECEPTOR ANTAGONISTS

Title (de)

TERTIÄRE AMIDOREXINREZEPTORANTAGONISTEN

Title (fr)

ANTAGONISTES DE RÉCEPTEURS D'OREXINES AMIDES TERTIAIRES

Publication

EP 2493299 A4 20130417 (EN)

Application

EP 10827347 A 20101022

Priority

  • US 25591609 P 20091029
  • US 2010053687 W 20101022

Abstract (en)

[origin: WO2011053522A1] The present invention is directed to tertiary amide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.

IPC 8 full level

A01N 37/18 (2006.01); A61K 31/16 (2006.01)

CPC (source: EP US)

A61P 3/04 (2017.12 - EP); A61P 25/00 (2017.12 - EP); C07D 213/81 (2013.01 - EP US)

Citation (search report)

  • [A] WO 2009016087 A1 20090205 - HOFFMANN LA ROCHE [CH], et al
  • [A] ROECKER A J ET AL: "Orexin receptor antagonists: Medicinal chemistry and therapeutic potential", CURRENT TOPICS IN MEDICINAL CHEMISTRY, BENTHAM SCIENCE PUBLISHERS LTD, NETHERLANDS, vol. 8, no. 11, 1 July 2008 (2008-07-01), pages 977 - 987, XP002504435, ISSN: 1568-0266, DOI: 10.2174/156802608784936746
  • [A] CAI J ET AL: "Antagonists of the orexin receptors", EXPERT OPINION ON THERAPEUTIC PATENTS, INFORMA HEALTHCARE, GB, vol. 16, no. 5, 1 May 2006 (2006-05-01), pages 631 - 646, XP002458093, ISSN: 1354-3776, DOI: 10.1517/13543776.16.5.631
  • See references of WO 2011053522A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2011053522 A1 20110505; EP 2493299 A1 20120905; EP 2493299 A4 20130417; US 2012196901 A1 20120802

DOCDB simple family (application)

US 2010053687 W 20101022; EP 10827347 A 20101022; US 201013500105 A 20101022