Global Patent Index - EP 2531185 A2

EP 2531185 A2 20121212 - COMBINATION THERAPY FOR TREATING CANCER COMPRISING AN IGF-1R INHIBITOR AND AN HDAC INHIBITOR

Title (en)

COMBINATION THERAPY FOR TREATING CANCER COMPRISING AN IGF-1R INHIBITOR AND AN HDAC INHIBITOR

Title (de)

KOMBINATIONSTHERAPIE ZUR KREBSBEHANDLUNG MIT EINEM IGF-1R-HEMMER UND EINEM HDAC-HEMMER

Title (fr)

POLYTHÉRAPIE DESTINÉE À TRAITER LE CANCER COMPRENANT UN INHIBITEUR DE L'IGF-1R ET UN INHIBITEUR DE LA HDAC

Publication

EP 2531185 A2 20121212 (EN)

Application

EP 11740231 A 20110131

Priority

  • US 30064310 P 20100202
  • US 2011023154 W 20110131

Abstract (en)

[origin: WO2011097166A2] The present invention relates to a method of treating cancer in a subject in need thereof, by administering to a subject in need thereof a first amount of an IGF-1R inhibitor in a first treatment procedure and a second amount of a histone deacetylase (HDAC) inhibitor or a pharmaceutically acceptable salt or hydrate thereof in a second treatment procedure. The first and second amounts together comprise a therapeutically effective amount.

IPC 8 full level

A61K 31/16 (2006.01); A61K 39/395 (2006.01)

CPC (source: EP)

A61K 31/167 (2013.01); A61K 39/395 (2013.01); A61K 45/06 (2013.01); C07K 16/2863 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01)

C-Set (source: EP)

  1. A61K 31/167 + A61K 2300/00
  2. A61K 39/395 + A61K 2300/00

Citation (search report)

See references of WO 2011097166A2

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

DOCDB simple family (publication)

WO 2011097166 A2 20110811; WO 2011097166 A9 20130725; EP 2531185 A2 20121212

DOCDB simple family (application)

US 2011023154 W 20110131; EP 11740231 A 20110131