EP 2545027 A1 20130116 - CRYSTALLINE SALTS AND/OR COCRYSTALS OF O-DESMETHYLTRAMADOL
Title (en)
CRYSTALLINE SALTS AND/OR COCRYSTALS OF O-DESMETHYLTRAMADOL
Title (de)
KRISTALLINE SALZE UND/ODER COKRISTALLE VON O-DESMETHYLTRAMADOL
Title (fr)
SELS CRISTALLINS ET/OU CO-CRISTAUX DE O-DESMÉTHYLTRAMADOL
Publication
Application
Priority
- EP 10002480 A 20100310
- EP 2011053542 W 20110309
- EP 11707666 A 20110309
Abstract (en)
[origin: WO2011110595A1] The present invention relates to salts present in crystalline form and/or to cocrystals of (+)- 3-[2-(dimethylamino)methyl-1-hydroxycyclohexyl]phenol or of (-)- 3-[2-(dimethylamino)methyl-1 -hydroxycyclohexyl]phenol containing cinnamic acid, C8- to C10-alkane monocarboxylic acids, C6- to C10-alkane dicarboxylic acids, C15- to C17-alkane monocarboxylic acids, fumaric acid, tartaric acid, mandelic acid, hippuric acid and/or embonic acid. It further relates to a method for the production thereof, to such salts and/or cocrystals for use as pharmaceuticals and to the use of salts and/or cocrystals for producing pharmaceuticals.
IPC 8 full level
C07C 215/64 (2006.01); A61K 31/135 (2006.01); A61P 25/00 (2006.01); C07C 53/126 (2006.01); C07C 55/20 (2006.01); C07C 57/15 (2006.01); C07C 57/44 (2006.01)
CPC (source: EP US)
A61P 1/12 (2017.12 - EP); A61P 11/14 (2017.12 - EP); A61P 13/10 (2017.12 - EP); A61P 21/00 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/30 (2017.12 - EP); A61P 29/00 (2017.12 - EP); C07C 53/126 (2013.01 - EP US); C07C 55/20 (2013.01 - EP US); C07C 57/15 (2013.01 - EP US); C07C 57/44 (2013.01 - EP US); C07C 215/64 (2013.01 - EP US); C07C 2601/14 (2017.04 - EP US)
Citation (search report)
See references of WO 2011110595A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2011110595 A1 20110915; EP 2545027 A1 20130116; US 2011251286 A1 20111013
DOCDB simple family (application)
EP 2011053542 W 20110309; EP 11707666 A 20110309; US 201113044069 A 20110309