EP 2545070 A1 20130116 - STAT3 ACTIVATION INHIBITORS
Title (en)
STAT3 ACTIVATION INHIBITORS
Title (de)
STAT3-AKTIVIERUNGS-HEMMER
Title (fr)
INHIBITEURS D'ACTIVATION DE STAT3
Publication
Application
Priority
- EP 10002535 A 20100310
- EP 2011001199 W 20110310
- EP 11707809 A 20110310
Abstract (en)
[origin: WO2011110359A1] The present invention relates to novel Stat3 activation inhibitors, especially to (poly)peptides capable to inhibit Stat3 signaling. The invention furthermore concerns nucleic acids encoding for these (poly)peptides and vectors comprising said nucleic acids. In addition, the present invention relates to respective uses of the Staß activation inhibitors and pharmaceutical compositions comprising same. The invention also relates to the isolated coiled-coil domain of Stat3 and screening methods for identifying compounds having affinity to this domain.
IPC 8 full level
A61K 38/17 (2006.01); C07K 14/47 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP)
C07K 14/4703 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 2011110359A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2011110359 A1 20110915; WO 2011110359 A8 20120510; EP 2545070 A1 20130116
DOCDB simple family (application)
EP 2011001199 W 20110310; EP 11707809 A 20110310