EP 2556826 A1 20130213 - Modified-release multiparticulate formulation of diltiazem HCL
Title (en)
Modified-release multiparticulate formulation of diltiazem HCL
Title (de)
Mehrteilchenformulierung von Diltiazem-HCL mit modifizierter Freisetzung
Title (fr)
Formulation multiparticulaire à libération modifiée de diltiazem HCL
Publication
Application
Priority
IT FI20110172 A 20110808
Abstract (en)
A multiparticulate formulation of diltiazem HCl is described which, in appropriate dosage and minimum volume, can be given as a single daily administration while guaranteeing, by means of appropriate sustained release, therapeutic levels of the drug throughout the course of the day. The formulation is characterised by microgranules having an extruded nucleus of diltiazem HCl surrounded by a layer of powdered diltiazem HCl, the whole coated with a sustained-released membrane based on ethyl cellulose and stearic acid.
IPC 8 full level
A61K 9/50 (2006.01); A61K 31/554 (2006.01)
CPC (source: EP)
A61K 9/5047 (2013.01); A61K 9/5073 (2013.01); A61K 31/554 (2013.01)
Citation (applicant)
- US 5344657 A 19940906 - DESMOLIN HENRI [FR]
- WO 2005016317 A1 20050224 - THEMIS LAB PRIVATE LTD [IN], et al
- WO 9723219 A1 19970703 - ETHYPHARM LAB PROD ETHIQUES [FR], et al
- US 2003003149 A1 20030102 - SHARMA VINAY K [US], et al
- US 7067151 B1 20060627 - HEINICKE GRANT W [AU], et al
- WO 0004883 A1 20000203 - ANDRX PHARMACEUTICALS INC [US]
- WO 9629992 A1 19961003 - ANDRX PHARMACEUTICALS INC [US]
- US 5622716 A 19970422 - BARTH DIETER [DE]
- WO 9300093 A1 19930107 - BIOVAIL RES CORP [CA], et al
Citation (search report)
- [IY] US 5670172 A 19970923 - BUXTON IAN RICHARD [GB], et al
- [Y] EP 1125586 A1 20010822 - TANABE SEIYAKU CO [JP]
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
EP 2556826 A1 20130213; EP 2556826 B1 20160921; ES 2607585 T3 20170403; IT FI20110172 A1 20130209; PT 2556826 T 20161228
DOCDB simple family (application)
EP 12179426 A 20120806; ES 12179426 T 20120806; IT FI20110172 A 20110808; PT 12179426 T 20120806