EP 2558479 A4 20130918 - METHOD FOR IMPROVING DETECTION OF B CELL IMMUNOGLOBULIN GENE RECOMBINATION
Title (en)
METHOD FOR IMPROVING DETECTION OF B CELL IMMUNOGLOBULIN GENE RECOMBINATION
Title (de)
VERFAHREN ZUM VERBESSERTEN NACHWEIS EINER B-ZELLEN-IMMUNGLOBULIN-GEN-REKOMBINATION
Title (fr)
PROCÉDÉ D'AMÉLIORATION DE LA DÉTECTION DE LA RECOMBINAISON DE GÈNES D'IMMUNOGLOBULINES DE LYMPHOCYTES B
Publication
Application
Priority
- US 31841710 P 20100329
- US 2011030398 W 20110329
Abstract (en)
[origin: WO2011123473A1] Disclosed is a method for generating primers to increase the yield of PCR products that represent the various genetic recombination events and antibodies that exist in a sample from a human or animal.
IPC 8 full level
C12Q 1/68 (2006.01)
CPC (source: EP)
C12Q 1/6853 (2013.01)
Citation (search report)
- [A] WO 0151661 A2 20010719 - AMSTERDAM SUPPORT DIAGNOSTICS [NL], et al
- [A] EP 0466520 A1 19920115 - LIFE TECHNOLOGIES INC [US]
- [XI] ESSONO S ET AL: "A general method allowing the design of oligonucleotide primers to amplify the variable regions from immunoglobulin cDNA", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 279, no. 1-2, 1 August 2003 (2003-08-01), pages 251 - 266, XP004455324, ISSN: 0022-1759, DOI: 10.1016/S0022-1759(03)00242-4
- [A] DONGEN VAN J J M ET AL: "Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936", LEUKEMIA, MACMILLAN PRESS LTD, US, vol. 17, no. 12, 1 December 2003 (2003-12-01), pages 2257 - 2317, XP002287366, ISSN: 0887-6924, DOI: 10.1038/SJ.LEU.2403202
- See references of WO 2011123473A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2011123473 A1 20111006; AU 2011235281 A1 20121122; CA 2794800 A1 20111006; CN 103154015 A 20130612; EP 2558479 A1 20130220; EP 2558479 A4 20130918; JP 2013523129 A 20130617
DOCDB simple family (application)
US 2011030398 W 20110329; AU 2011235281 A 20110329; CA 2794800 A 20110329; CN 201180024420 A 20110329; EP 11763339 A 20110329; JP 2013502769 A 20110329