Global Patent Index - EP 2560977 A4

EP 2560977 A4 20131127 - NEW AG(I) COMPOUNDS WITH CHELATING LIGANDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS

Title (en)

NEW AG(I) COMPOUNDS WITH CHELATING LIGANDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS

Title (de)

NEUE AG(I)-VERBINDUNGEN MIT CHELATBILDENDEN LIGANDEN UND IHRE VERWENDUNG IN PHARMAZEUTISCHEN ZUSAMMENSETZUNGEN

Title (fr)

NOUVEAUX COMPOSÉS DE AG(I) AVEC LIGANDS CHÉLATANTS ET LEUR EMPLOI DANS DES COMPOSITIONS PHARMACEUTIQUES

Publication

EP 2560977 A4 20131127 (EN)

Application

EP 11772330 A 20110421

Priority

  • SE 1000411 A 20100422
  • SE 2011050492 W 20110421

Abstract (en)

[origin: WO2011133104A1] The present invention relates to new Ag(I) complexes with (E)-picolinaldehyde oxime, 4,5-diazafluorenone and their derivatives and related chelating pyridine based ligands, and their use in antimicrobial compositions.

IPC 8 full level

A61K 31/15 (2006.01); A61K 33/38 (2006.01); A61P 31/04 (2006.01); C07F 1/10 (2006.01)

CPC (source: EP)

A61K 31/15 (2013.01); A61K 33/38 (2013.01); A61P 31/04 (2017.12); C07F 1/005 (2013.01)

Citation (search report)

  • [X] DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; ESHWIKA, AHMED ET AL: "Metal complexes of 1,10-phenanthroline-5,6-dione alter the susceptibility of the yeast Candida albicans to amphotericin B and miconazole", XP002714384, retrieved from STN Database accession no. 2004:438748 & ESHWIKA, AHMED ET AL: "Metal complexes of 1,10-phenanthroline-5,6-dione alter the susceptibility of the yeast Candida albicans to amphotericin B and miconazole", BIOMETALS , 17(4), 415-422 CODEN: BOMEEH; ISSN: 0966-0844, 2004
  • [X] A OYA ET AL: "Preparation of an antibacterial ceramic filter from montmorillonite supporting silver chelate of 2,2'-dipyridyl", APPLIED CLAY SCIENCE, vol. 8, no. 5, 1 January 1994 (1994-01-01), pages 365 - 371, XP055082703, ISSN: 0169-1317, DOI: 10.1016/0169-1317(94)90025-6
  • [X] FUMIHIKO OHASHI ET AL: "Antimicrobial and antifungal agents derived from clay minerals (II): properties of montmorillonite supported by silver chelates of 1,10-phenanthroline and 2,2'-dipyridyl", APPLIED CLAY SCIENCE, vol. 6, no. 4, 1 January 1992 (1992-01-01), pages 301 - 310, XP055082704, ISSN: 0169-1317, DOI: 10.1016/S0169-1317(09)90005-9
  • [X] F YILMAZ: "5,5-Diethylbarbiturate Complexes of Silver with 2,2'-Bipyridine and 3-(2-Pyridyl)propanol: Syntheses, Crystal Structures, Spectroscopic, Thermal and Antimicrobial Activity Studies", ZEITSCHRIFT FUER NATURFORSCHUNG, TEIL B: CHEMICAL SCIENCES, vol. 63b, 1 January 2008 (2008-01-01), pages 134 - 138, XP055082684
  • [X] DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; WANG, YOUXIANG ET AL: "Syntheses and Electrochemical, Photophysical, and Photochemical Properties of Ruthenium(II) 4,5-Diazafluorenone Complexes and Their Ketal Derivatives", XP002714382, retrieved from STN Database accession no. 1998:229743 & YOUXIANG WANG ET AL: "Syntheses and Electrochemical, Photophysical, and Photochemical Properties of Ruthenium(II) 4,5-Diazafluorenone Complexes and Their Ketal Derivatives", INORGANIC CHEMISTRY, vol. 37, no. 8, 1 April 1998 (1998-04-01), pages 2051 - 2059, XP055082682, ISSN: 0020-1669, DOI: 10.1021/ic970987e
  • [X] DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; ONUEGBU, JONATHAN ET AL: "Acetato(1,10-phenanthroline-5,6-dione)silver(I) trihydrate", XP002714383, retrieved from STN Database accession no. 2008:148784 & ONUEGBU, JONATHAN ET AL: "Acetato(1,10-phenanthroline-5,6-dione)silver(I) trihydrate", ACTA CRYSTALLOGRAPHICA, SECTION E: STRUCTURE REPORTS ONLINE , 64(2), M403-M404, M403/1-M403/9 CODEN: ACSEBH; ISSN: 1600-5368 URL: HTTP://JOURNALS.IUCR.ORG/E/ISSUES/2008/02/00/CI2544/CI2544.PDF, 2008
  • [X] RODNEY P. FEAZELL ET AL: "Variability in the Structures of Luminescent [2-(Aminomethyl)pyridine]silver(I) Complexes: Effect of Ligand Ratio, Anion, Hydrogen Bonding, and [pi]-Stacking", EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, vol. 2005, no. 16, 1 August 2005 (2005-08-01), pages 3287 - 3297, XP055082688, ISSN: 1434-1948, DOI: 10.1002/ejic.200500215
  • [X] ANNA BELLUSCI ET AL: "Anion dependent mesomorphism in coordination networks based on 2,2'-bipyridine silver(i) complexes", DALTON TRANSACTIONS, no. 36, 1 January 2009 (2009-01-01), pages 7381, XP055082691, ISSN: 1477-9226, DOI: 10.1039/b906178a
  • [XP] MORSY A. M. ABU-YOUSSEF ET AL: "Synthesis, Crystal Structure, Quantum Chemical Calculations, DNA Interactions, and Antimicrobial Activity of [Ag(2-amino-3-methylpyridine) 2 ]NO 3 and [Ag(pyridine-2-carboxaldoxime)NO 3 ]", INORGANIC CHEMISTRY, vol. 49, no. 21, 1 November 2010 (2010-11-01), pages 9788 - 9797, XP055082683, ISSN: 0020-1669, DOI: 10.1021/ic100581k
  • See references of WO 2011133104A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2011133104 A1 20111027; EP 2560977 A1 20130227; EP 2560977 A4 20131127

DOCDB simple family (application)

SE 2011050492 W 20110421; EP 11772330 A 20110421