EP 2563121 A1 20130306 - METHODS AND COMPOSITIONS FOR PROTECTING AGAINST NEUROTOXIC AGENTS
Title (en)
METHODS AND COMPOSITIONS FOR PROTECTING AGAINST NEUROTOXIC AGENTS
Title (de)
VERFAHREN UND ZUSAMMENSETZUNGEN ZUM SCHUTZ GEGEN NERVENGIFTE
Title (fr)
MÉTHODES ET COMPOSITIONS DE PROTECTION CONTRE DES AGENTS NEUROTOXIQUES
Publication
Application
Priority
- US 201161454409 P 20110318
- US 41389910 P 20101115
- US 77147610 A 20100430
- US 2011034508 W 20110429
Abstract (en)
[origin: WO2011137317A1] Provided are methods for protecting against or reducing neurotoxicity of exposure to a neurotoxic agent, comprising administering an electrokinetically altered aqueous fluid as provided herein in an amount sufficient to provide for neuroprotection against the neurotoxic agent, preferably where protecting against or reducing loss of motor coordination in the subject exposed to the neurotoxin is afforded. In certain aspects, protecting or reducing neurotoxin-mediated neuronal apoptosis is afforded, and/or activating or inducing at least one of PI-3 kinase and Akt phosphorylation in neurons is afforded. Preferably, administering the fluid comprises administering the fluid prior to exposure to the neurotoxic agent. Additionally provided are methods for preserving or improving motor coordination in a subject having a neurodegenerative condition or disease, comprising administering an electrokinetically altered aqueous fluid as provided herein in an amount sufficient to provide for preserving or improving motor coordination in the subject.
IPC 8 full level
A01N 39/00 (2006.01)
CPC (source: EP KR)
A61K 9/0019 (2013.01 - EP); A61K 9/14 (2013.01 - KR); A61K 9/16 (2013.01 - KR); A61K 31/522 (2013.01 - EP); A61K 31/56 (2013.01 - EP KR); A61K 31/58 (2013.01 - EP); A61K 38/13 (2013.01 - EP); A61K 41/0004 (2013.01 - EP); A61K 45/06 (2013.01 - EP); A61P 9/10 (2017.12 - EP); A61P 17/02 (2017.12 - EP); A61P 21/00 (2017.12 - EP); A61P 21/02 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/06 (2017.12 - EP); A61P 25/14 (2017.12 - EP); A61P 25/16 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 31/18 (2017.12 - EP); A61P 39/00 (2017.12 - EP); A61P 39/02 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2011137317 A1 20111103; AU 2011245223 A1 20130110; AU 2011245223 B2 20151119; BR 112012027905 A2 20150908; CA 2798127 A1 20111103; CN 103002734 A 20130327; EA 201201483 A1 20130430; EP 2563121 A1 20130306; EP 2563121 A4 20160511; IL 222757 A0 20121231; JP 2013529195 A 20130718; JP 5941908 B2 20160629; KR 20130113314 A 20131015; MX 2012012634 A 20130226
DOCDB simple family (application)
US 2011034508 W 20110429; AU 2011245223 A 20110429; BR 112012027905 A 20110429; CA 2798127 A 20110429; CN 201180031803 A 20110429; EA 201201483 A 20110429; EP 11775615 A 20110429; IL 22275712 A 20121029; JP 2013508277 A 20110429; KR 20127031216 A 20110429; MX 2012012634 A 20110429