EP 2571856 A1 20130327 - COMPOUNDS
Title (en)
COMPOUNDS
Title (de)
VERBINDUNGEN
Title (fr)
COMPOSÉS
Publication
Application
Priority
- GB 201008210 A 20100517
- EP 2011057900 W 20110516
Abstract (en)
[origin: WO2011144577A1] A compound of formula (I) or a pharmaceutically acceptable salt or prodrug thereof: wherein R1 is CN; R2 is H or F; R3 and R4 are independently hydrogen, fluorine, chlorine or OR8; R5 is hydrogen, C1-6 alkyl, C1-6 alkenyl or C1-6 alkynyl; R6 and R7 are independently hydrogen, halogen, OR8 or NR9R10; R8 is hydrogen or C1-6 alkyl; R9 and R10 are independently hydrogen or C1-6 alkyl; or the groups R9 and R10 when they are attached to a nitrogen atom may together form a 5- or 6-membered ring which optionally contains one further heteroatom selected from NR8, S and O said 5 or 6 membered ring being optionally substituted by hydroxyl or C1-6 alkoxy; or the groups R9 and R10 when they are attached to a nitrogen atom may together form an azetidinyl ring optionally substituted by hydroxyl or C1-6 alkoxy, is provided. The use of such compounds in treating amyloid-related disease is also disclosed.
IPC 8 full level
C07D 239/47 (2006.01); A61K 31/505 (2006.01); A61P 25/28 (2006.01)
CPC (source: EP KR)
A61K 31/505 (2013.01 - KR); A61P 3/10 (2017.12 - EP); A61P 13/08 (2017.12 - EP); A61P 21/02 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/14 (2017.12 - EP); A61P 25/16 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 27/12 (2017.12 - EP); A61P 35/00 (2017.12 - EP); C07D 239/47 (2013.01 - EP KR)
Citation (search report)
See references of WO 2011144577A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2011144577 A1 20111124; AU 2011254668 A1 20121206; CA 2799556 A1 20111124; EP 2571856 A1 20130327; GB 201008210 D0 20100630; JP 2013526555 A 20130624; KR 20130109936 A 20131008
DOCDB simple family (application)
EP 2011057900 W 20110516; AU 2011254668 A 20110516; CA 2799556 A 20110516; EP 11721742 A 20110516; GB 201008210 A 20100517; JP 2013510586 A 20110516; KR 20127030829 A 20110516