EP 2571880 A1 20130327 - PYRROLO [2, 3 - B]PYRAZINE - 7 - CARBOXAMIDE DERIVATIVES AND THEIR USE AS JAK AND SYK INHIBITORS
Title (en)
PYRROLO [2, 3 - B]PYRAZINE - 7 - CARBOXAMIDE DERIVATIVES AND THEIR USE AS JAK AND SYK INHIBITORS
Title (de)
PYRROLO [2, 3 - B]PYRAZIN - 7 - CARBOXAMIDDERIVATE UND IHRE VERWENDUNG ALS JAK- UND SYK-HEMMER
Title (fr)
DÉRIVÉS DE PYRROLO[2,3-B]PYRAZINE-7-CARBOXAMIDE ET LEUR UTILISATION COMME INHIBITEURS DE JAK ET SYK
Publication
Application
Priority
- US 201161475281 P 20110414
- US 34650310 P 20100520
- EP 2011057911 W 20110517
Abstract (en)
[origin: US2011288067A1] The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables Q and R, R2, and R3 are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.
IPC 8 full level
C07D 487/04 (2006.01); A61K 31/4985 (2006.01); A61P 29/00 (2006.01); A61P 37/00 (2006.01); C07D 519/00 (2006.01)
CPC (source: EP KR US)
A61K 31/4985 (2013.01 - KR); A61P 1/00 (2017.12 - EP); A61P 1/04 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 5/14 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 11/06 (2017.12 - EP); A61P 17/00 (2017.12 - EP); A61P 17/04 (2017.12 - EP); A61P 17/06 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 19/04 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 35/02 (2017.12 - EP); A61P 37/00 (2017.12 - EP); A61P 37/02 (2017.12 - EP); A61P 37/04 (2017.12 - EP); A61P 37/06 (2017.12 - EP); C07D 487/04 (2013.01 - EP KR US); C07D 519/00 (2013.01 - EP US)
Citation (search report)
See references of WO 2011144585A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
US 2011288067 A1 20111124; AR 081204 A1 20120704; BR 112012029437 A2 20170307; CA 2799904 A1 20111124; CN 103003281 A 20130327; EP 2571880 A1 20130327; JP 2013529204 A 20130718; KR 20130083386 A 20130722; MX 2012013378 A 20130124; RU 2012152352 A 20140627; US 2014155376 A1 20140605; WO 2011144585 A1 20111124
DOCDB simple family (application)
US 201113110062 A 20110518; AR P110101698 A 20110518; BR 112012029437 A 20110517; CA 2799904 A 20110517; CN 201180035015 A 20110517; EP 11719576 A 20110517; EP 2011057911 W 20110517; JP 2013510592 A 20110517; KR 20127032866 A 20110517; MX 2012013378 A 20110517; RU 2012152352 A 20110517; US 201414172144 A 20140204