EP 2576799 A1 20130410 - PRODUCTION OF FATTY ACIDS BY HETEROLOGOUS EXPRESSION OF GENE CLUSTERS FROM MYXOBACTERIA
Title (en)
PRODUCTION OF FATTY ACIDS BY HETEROLOGOUS EXPRESSION OF GENE CLUSTERS FROM MYXOBACTERIA
Title (de)
HERSTELLUNG VON FETTSÄUREN DURCH HETEROLOGE EXPRESSION VON GENCLUSTERN AUS MYXOBAKTERIEN
Title (fr)
PRODUCTION D'ACIDES GRAS PAR L'EXPRESSION HÉTÉROLOGUE DE GROUPES DE GÈNES À PARTIR DE MYXOBACTÉRIES
Publication
Application
Priority
- EP 10005644 A 20100531
- EP 2011058863 W 20110530
- EP 11721794 A 20110530
Abstract (en)
[origin: EP2390343A1] The invention relates to a process for producing one or more polyunsaturated fatty acids by means of heterologous gene expression, the process comprising the steps: (i) providing a production organism which comprises a gene cluster encoding a polyunsaturated fatty acid biosynthetic pathway, said gene cluster - being derived from a source organism which differs from the production organism; and - encompassing a subsequence ER encoding an enoylreductase and a subsequence AT encoding an acyltransferase, wherein the subsequence AT is located downstream with respect to the subsequence ER; (ii) growing the production organism of step (i) in the presence of a fermentable carbon source whereby one or more polyunsaturated fatty acids are produced; and (iii) optionally, recovering the one or more polyunsaturated fatty acids.
IPC 8 full level
C12P 7/6427 (2022.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 15/52 (2006.01); C12P 7/6432 (2022.01); C12P 7/6434 (2022.01)
CPC (source: EP US)
C12N 9/001 (2013.01 - EP US); C12N 9/1029 (2013.01 - EP US); C12N 15/52 (2013.01 - EP US); C12P 7/64 (2013.01 - EP US); C12P 7/6427 (2013.01 - EP US); C12P 7/6432 (2022.01 - EP US); C12P 7/6434 (2022.01 - EP US); C12Y 103/01009 (2013.01 - EP US); C12Y 203/01051 (2013.01 - EP US); Y02P 20/52 (2015.11 - US)
Citation (search report)
See references of WO 2011151298A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 2390343 A1 20111130; DK 2576799 T3 20170807; EP 2576799 A1 20130410; EP 2576799 B1 20170426; ES 2633587 T3 20170922; JP 2013529912 A 20130725; JP 2016136962 A 20160804; JP 6200807 B2 20170927; PT 2576799 T 20170713; US 2013196391 A1 20130801; US 2016017388 A1 20160121; US 9127298 B2 20150908; US 9574215 B2 20170221; WO 2011151298 A1 20111208
DOCDB simple family (application)
EP 10005644 A 20100531; DK 11721794 T 20110530; EP 11721794 A 20110530; EP 2011058863 W 20110530; ES 11721794 T 20110530; JP 2013512859 A 20110530; JP 2016036413 A 20160226; PT 11721794 T 20110530; US 201113701411 A 20110530; US 201514812759 A 20150729