EP 2579883 A1 20130417 - BACTERIOPHAGES FOR USE AGAINST BACTERIAL INFECTIONS
Title (en)
BACTERIOPHAGES FOR USE AGAINST BACTERIAL INFECTIONS
Title (de)
BAKTERIOPHAGEN ZUR VERWENDUNG GEGEN BAKTERIELLE INFEKTIONEN
Title (fr)
BACTÉRIOPHAGES DESTINÉS À ÊTRE UTILISÉS CONTRE DES INFECTIONS BACTÉRIENNES
Publication
Application
Priority
- DK PA201000492 A 20100608
- DK 2011050201 W 20110608
Abstract (en)
[origin: WO2011154007A1] The present invention relates to a composition comprising obligate lytic bacteriophages generated by a method comprising subjecting normally in vivo lysogenic, pseudolysogenic or temperate bacteriophages to genetic modifications in vitro, which alters the biological activity of one or more of the individual gene products for establishing, maintaining, controlling or regulating the lysogenic life cycle of the bacteriophages, thereby converting them to obligate lytic bacteriophages, wherein the genetic modification includes modification of a single gene in the operon containing a gene resulting in a gene product for establishing, maintaining, controlling or regulating the lysogenic life cycle of the bacteriophages.
IPC 8 full level
A61K 35/76 (2006.01); A61P 31/04 (2006.01)
CPC (source: EP US)
A61K 35/76 (2013.01 - EP US); A61P 31/04 (2017.12 - EP); C12N 7/00 (2013.01 - US); C12Q 1/04 (2013.01 - US); C12N 2795/00021 (2013.01 - EP US); C12N 2795/00032 (2013.01 - EP US); C12N 2795/00033 (2013.01 - US); C12N 2795/00051 (2013.01 - US); C12N 2795/10121 (2013.01 - EP US); C12N 2795/10322 (2013.01 - EP US); Y02A 50/30 (2017.12 - EP)
Citation (search report)
See references of WO 2011154007A1
Citation (examination)
- KARIN L HECKMAN ET AL: "Gene splicing and mutagenesis by PCR-driven overlap extension", NATURE PROTOCOLS, vol. 2, no. 4, 1 April 2007 (2007-04-01), pages 924 - 932, XP055191276, ISSN: 1750-2799, DOI: 10.1038/nprot.2007.132
- K. H. LYNCH ET AL: "Inactivation of Burkholderia cepacia Complex Phage KS9 gp41 Identifies the Phage Repressor and Generates Lytic Virions", JOURNAL OF VIROLOGY., vol. 84, no. 3, 1 February 2010 (2010-02-01), US, pages 1276 - 1288, XP055249641, ISSN: 0022-538X, DOI: 10.1128/JVI.01843-09
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2011154007 A1 20111215; EP 2579883 A1 20130417; US 2013121967 A1 20130516; US 2015247127 A1 20150903
DOCDB simple family (application)
DK 2011050201 W 20110608; EP 11726059 A 20110608; US 201113702599 A 20110608; US 201514635598 A 20150302