EP 2579891 A2 20130417 - METHODS OF MITIGATING EFFECTS OF RADIATION AND REDUCING THE RISK OF SYSTEMIC INFECTION
Title (en)
METHODS OF MITIGATING EFFECTS OF RADIATION AND REDUCING THE RISK OF SYSTEMIC INFECTION
Title (de)
VERFAHREN ZUR ABSCHWÄCHUNG VON STRAHLUNGSWIRKUNGEN UND VERRINGERUNG DES RISIKOS EINER SYSTEMISCHEN INFEKTION
Title (fr)
MÉTHODES D'ATTÉNUATION DES EFFETS DE RAYONNEMENT ET DE RÉDUCTION DU RISQUE D'INFECTION SYSTÉMIQUE
Publication
Application
Priority
- US 35406710 P 20100611
- US 2011040006 W 20110610
Abstract (en)
[origin: WO2011156729A2] The present invention is directed to methods of reducing mortality in a subject exposed to a lethal dose of radiation comprising administering to the subject an effective amount of a thrombin peptide derivative described herein. Also included are methods of reducing the risk of developing bacterial, fungal or viral systemic infection a subject who is exposed or not exposed to radiation, methods of treating a subject with traumatic injury, dermal injury and/or bum injury who is also exposed to radiation, methods of reducing radiation related injury in a subject undergoing radiation therapy, methods of reducing the risk of developing a radiation induced illness, and methods of promoting the healing of a wound that is caused by radiation exposure and/or has been exposed to radiation. These methods comprising administering to the subject an effective amount of a thrombin peptide derivative described herein.
IPC 8 full level
A61K 38/48 (2006.01)
CPC (source: EP)
A61K 38/4833 (2013.01); A61P 17/02 (2017.12); A61P 31/04 (2017.12); A61P 31/10 (2017.12); A61P 31/12 (2017.12); A61P 37/04 (2017.12); A61P 39/00 (2017.12)
Citation (search report)
See references of WO 2011156729A2
Citation (examination)
WO 2008036387 A2 20080327 - ORTHOLOGIC CORP [US], et al
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2011156729 A2 20111215; WO 2011156729 A3 20120510; AU 2011265228 A1 20130523; CA 2802176 A1 20111215; EP 2579891 A2 20130417; JP 2013529600 A 20130722
DOCDB simple family (application)
US 2011040006 W 20110610; AU 2011265228 A 20110610; CA 2802176 A 20110610; EP 11728735 A 20110610; JP 2013514392 A 20110610