EP 2588106 A4 20140101 - SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITION CONTAINING PRAMIPEXOLE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF WITH IMPROVED STABILITY
Title (en)
SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITION CONTAINING PRAMIPEXOLE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF WITH IMPROVED STABILITY
Title (de)
VERZÖGERT FREIGESETZTE PHARMAZEUTISCHE ZUSAMMENSETZUNG MIT PRAMIPEXOL ODER EINEM PHARMAZEUTISCH ZULÄSSIGEN SALZ DAVON MIT ERHÖHTER STABILITÄT
Title (fr)
COMPOSITION PHARMACEUTIQUE À LIBÉRATION PROLONGÉE CONTENANT DU PRAMIPEXOLE, OU L'UN DE SES SELS PHARMACEUTIQUEMENT ACCEPTABLES, PRÉSENTANT UNE MEILLEURE STABILITÉ
Publication
Application
Priority
- KR 20100064044 A 20100702
- KR 2011003515 W 20110512
Abstract (en)
[origin: WO2012002644A2] Disclosed is a sustained-release pharmaceutical composition containing pramipexole or a pharmaceutically acceptable salt thereof and, more particularly, a pharmaceutical composition that uses a stabilizer for inhibiting production of related substances caused by additives and greatly enhances stability. The pharmaceutical composition shows an effectively controlled dissolution profile, realizing its usefulness in the manufacture of pramipexole-containing sustained-release preparations in various dosage forms easy for drug release control; includes a stabilizer to minimize impurity production of the drug-containing products during drug storage, remarkably improving chemical stability; and thereby eliminates a need for separate studies on the physical chemical structure analysis and/or on the toxicological effects of the corresponding impurities.
IPC 8 full level
A61K 9/20 (2006.01); A61K 9/22 (2006.01); A61K 31/425 (2006.01); A61K 47/38 (2006.01)
CPC (source: EP)
A61K 9/2027 (2013.01); A61K 9/2054 (2013.01); A61K 31/425 (2013.01); A61P 25/16 (2017.12); A61P 25/18 (2017.12)
Citation (search report)
- [XI] WO 2009152041 A2 20091217 - SUPERNUS PHARMACEUTICALS INC [US], et al
- [XI] WO 2007054976 A2 20070518 - PANACEA BIOTEC LTD [IN], et al
- [XI] WO 2007002518 A1 20070104 - SPHERICS INC [US], et al
- [X] EP 0428038 A2 19910522 - BOEHRINGER INGELHEIM KG [DE], et al
- [XP] WO 2011037976 A2 20110331 - REDDYS LAB LTD DR [IN], et al
- See references of WO 2012002644A2
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2012002644 A2 20120105; WO 2012002644 A3 20120412; EP 2588106 A2 20130508; EP 2588106 A4 20140101; JP 2013530212 A 20130725; KR 101307334 B1 20130912; KR 20120003278 A 20120110
DOCDB simple family (application)
KR 2011003515 W 20110512; EP 11801051 A 20110512; JP 2013518223 A 20110512; KR 20100064044 A 20100702