EP 2593787 B1 20180704 - A METHOD OF ANALYSING A BLOOD SAMPLE OF A SUBJECT FOR THE PRESENCE OF A DISEASE MARKER
Title (en)
A METHOD OF ANALYSING A BLOOD SAMPLE OF A SUBJECT FOR THE PRESENCE OF A DISEASE MARKER
Title (de)
VERFAHREN ZUR ANALYSE EINER BLUTPROBE AUF DAS VORHANDENSEIN EINES KRANKEITS-MARKERS
Title (fr)
MÉTHODE D'ANALYSER UNE PRISE DE SANG D'UN SUJET POUR LA PRÉSENCE D'UN MARQUEUR DE LA MALADIE
Publication
Application
Priority
- EP 11167973 A 20110527
- EP 11158912 A 20110318
- US 36483110 P 20100716
- EP 10169897 A 20100716
- NL 2011050518 W 20110715
- EP 11736199 A 20110715
Abstract (en)
[origin: WO2012008839A2] The present invention relates to a method of analysing a blood sample of a subject for the presence of a disease marker, said method comprising the steps of a) extracting nucleic acid from anucleated blood cells in said blood sample to provide an anucleated blood cells-extracted nucleic acid fraction, and b) analysing said anucleated blood cells-extracted nucleic acid fraction for the presence of a disease marker, wherein said disease marker is a disease-specific mutation in a gene of a cell of said subject, or wherein said disease marker is a disease-specific expression profile of genes of a cell of said subject.
IPC 8 full level
G01N 33/48 (2006.01)
CPC (source: EP US)
A61P 35/00 (2017.12 - EP); A61P 35/02 (2017.12 - EP); C12Q 1/6827 (2013.01 - US); C12Q 1/6886 (2013.01 - EP US); C12Q 2600/112 (2013.01 - EP US); C12Q 2600/158 (2013.01 - EP US)
Citation (examination)
- M. GIRARDOT ET AL: "miR-28 is a thrombopoietin receptor targeting microRNA detected in a fraction of myeloproliferative neoplasm patient platelets", BLOOD, vol. 116, no. 3, 22 July 2010 (2010-07-22), US, pages 437 - 445, XP055233023, ISSN: 0006-4971, DOI: 10.1182/blood-2008-06-165985
- CALVERLEY DAVID C ET AL: "Significant Downregulation of Platelet Gene Expression in Metastatic Lung Cancer", CTS-CLINICAL AND TRANSLATIONAL SCIENCE, vol. 3, no. 5, October 2010 (2010-10-01), pages 227 - 232, ISSN: 1752-8054(print)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2012008839 A2 20120119; WO 2012008839 A3 20120301; WO 2012008839 A9 20120503; AU 2011277178 A1 20130131; AU 2011277178 A2 20130207; AU 2011277178 B2 20161020; BR 112013001136 A2 20160705; BR 112013001136 B1 20201215; CA 2805586 A1 20120119; CA 2805586 C 20200901; CN 103168235 A 20130619; CN 103168235 B 20160113; EP 2593787 A2 20130522; EP 2593787 B1 20180704; HK 1186767 A1 20140321; JP 2013534429 A 20130905; JP 2017018099 A 20170126; JP 6076901 B2 20170215; JP 6171057 B2 20170726; MX 2013000606 A 20130628; MX 351242 B 20171005; SG 187101 A1 20130228; US 10174364 B2 20190108; US 2013196873 A1 20130801
DOCDB simple family (application)
NL 2011050518 W 20110715; AU 2011277178 A 20110715; BR 112013001136 A 20110715; CA 2805586 A 20110715; CN 201180044900 A 20110715; EP 11736199 A 20110715; HK 13114039 A 20131218; JP 2013519616 A 20110715; JP 2016133808 A 20160706; MX 2013000606 A 20110715; SG 2013003553 A 20110715; US 201113809960 A 20110715