Global Patent Index - EP 2601181 A1

EP 2601181 A1 20130612 - ACID ADDITION SALTS OF THE 2-[2-[[(4-METHOXY-2,6-DIMETHYLPHENYL)SULFONYL]-(METHYL)AMINO]ETHOXY]-N-METHYL-N-[3-(4-METHYLPIPERAZIN-1-YL)CYCLOHEXYL]ACETAMIDE AND THE USE THEREOF AS BRADYKININ B1 RECEPTOR ANTAGONISTS

Title (en)

ACID ADDITION SALTS OF THE 2-[2-[[(4-METHOXY-2,6-DIMETHYLPHENYL)SULFONYL]-(METHYL)AMINO]ETHOXY]-N-METHYL-N-[3-(4-METHYLPIPERAZIN-1-YL)CYCLOHEXYL]ACETAMIDE AND THE USE THEREOF AS BRADYKININ B1 RECEPTOR ANTAGONISTS

Title (de)

SÄUREADDITIONSSALZE DES 2-[2-[[(4-METHOXY-2,6-DIMETHYLPHENYL)SULFONYL]-(METHYL)AMINO]ETHOXY]-N-METHYL-N-[3-(4-METHYLPIPERAZIN-1-YL)CYCLOHEXYL]ACETAMIDS UND IHRE VERWENDUNG ALS BRADYKININ-B1 REZEPTOR ANTAGONISTEN

Title (fr)

SELS D'ADDITION D'ACIDE DU 2-[2-[[(4-MÉTHOXY-2,6-DIMÉTHYLPHÉNYL)SULFONYL]-(MÉTHYL)AMINO]ÉTHOXY]-N-MÉTHYL-N-[3-(4-MÉTHYLPIPÉRAZINE-1-YL)CYCLOHEXYL]ACÉTAMIDE, ET LEUR UTILISATION EN TANT QU'ANTAGONISTES DU RÉCEPTEUR DE LA BRADYKININE-B1

Publication

EP 2601181 A1 20130612 (DE)

Application

EP 11741454 A 20110804

Priority

  • EP 10172018 A 20100805
  • EP 2011063413 W 20110804
  • EP 11741454 A 20110804

Abstract (en)

[origin: WO2012017027A1] The invention relates to the novel acid addition salts AB of the following free base of formula (A) or the enantiomer thereof with a physiologically acceptable acid B selected from the group consisting of hydrochloric acid, fumaric acid, and tartaric acid and to the polymorphs, hydrates, and solvates thereof.

IPC 8 full level

C07D 295/135 (2006.01); A61K 31/495 (2006.01); A61P 29/00 (2006.01)

CPC (source: EP US)

A61P 1/02 (2018.01 - EP); A61P 1/04 (2018.01 - EP); A61P 1/18 (2018.01 - EP); A61P 3/04 (2018.01 - EP); A61P 3/10 (2018.01 - EP); A61P 7/10 (2018.01 - EP); A61P 9/00 (2018.01 - EP); A61P 9/10 (2018.01 - EP); A61P 9/12 (2018.01 - EP); A61P 11/00 (2018.01 - EP); A61P 11/02 (2018.01 - EP); A61P 11/06 (2018.01 - EP); A61P 13/02 (2018.01 - EP); A61P 13/10 (2018.01 - EP); A61P 13/12 (2018.01 - EP); A61P 17/02 (2018.01 - EP); A61P 17/06 (2018.01 - EP); A61P 19/00 (2018.01 - EP); A61P 21/00 (2018.01 - EP); A61P 25/04 (2018.01 - EP); A61P 25/24 (2018.01 - EP); A61P 27/02 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 31/04 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 295/135 (2013.01 - EP); C07D 295/155 (2013.01 - EP US)

Citation (search report)

See references of WO 2012017027A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2012017027 A1 20120209; AU 2011287581 A1 20130214; CA 2807078 A1 20120209; CN 103003253 A 20130327; EP 2601181 A1 20130612; JP 2013535480 A 20130912; MX 2013000978 A 20130215; US 2013289049 A1 20131031

DOCDB simple family (application)

EP 2011063413 W 20110804; AU 2011287581 A 20110804; CA 2807078 A 20110804; CN 201180035544 A 20110804; EP 11741454 A 20110804; JP 2013522248 A 20110804; MX 2013000978 A 20110804; US 201113814006 A 20110804