EP 2605768 A2 20130626 - SYNERGISTIC ACTIVITY OF MODULATORS OF THE NO METABOLISM AND OF NADPH OXIDASE IN THE SENSITIZATION OF TUMOUR CELLS
Title (en)
SYNERGISTIC ACTIVITY OF MODULATORS OF THE NO METABOLISM AND OF NADPH OXIDASE IN THE SENSITIZATION OF TUMOUR CELLS
Title (de)
SYNERGISTISCHE WIRKUNG VON MODULATOREN DES NO-STOFFWECHSELS UND DER NADPH-OXIDASE BEI DER SENSITIVIERUNG VON TUMORZELLEN
Title (fr)
EFFET SYNERGIQUE DE MODULATEURS DU MÉTABOLISME DE NO ET DE LA NADPH OXYDASE LORS DE LA SENSIBILISATION DE CELLULES TUMORALES
Publication
Application
Priority
- EP 10173500 A 20100820
- EP 2011063742 W 20110810
- EP 11741234 A 20110810
Abstract (en)
[origin: EP2422777A1] Pharmaceutical composition comprises at least an active substance (A), which increases the available nitric oxide concentration in the cell and at least one active substance (B) which stimulates the NADPH oxidase. ACTIVITY : Cytostatic. MECHANISM OF ACTION : NADPH oxidase stimulator; Nitric oxide synthase stimulator. Test details are described but no results given.
IPC 8 full level
A61K 31/05 (2006.01); A61K 31/198 (2006.01); A61K 31/53 (2006.01)
CPC (source: EP US)
A61K 31/05 (2013.01 - EP US); A61K 31/105 (2013.01 - US); A61K 31/198 (2013.01 - EP US); A61K 31/337 (2013.01 - US); A61K 31/352 (2013.01 - US); A61K 31/427 (2013.01 - US); A61K 31/53 (2013.01 - EP US); A61K 38/18 (2013.01 - US); A61K 38/217 (2013.01 - US)
Citation (search report)
See references of WO 2012022659A2
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 2422777 A1 20120229; EP 2605768 A2 20130626; US 2013171104 A1 20130704; US 2016220542 A1 20160804; WO 2012022659 A2 20120223; WO 2012022659 A3 20120412; WO 2012022659 A9 20120531
DOCDB simple family (application)
EP 10173500 A 20100820; EP 11741234 A 20110810; EP 2011063742 W 20110810; US 201113818089 A 20110810; US 201614945134 A 20160204