EP 2606132 A1 20130626 - C6ORF167 AS A TARGET GENE FOR CANCER THERAPY AND DIAGNOSIS
Title (en)
C6ORF167 AS A TARGET GENE FOR CANCER THERAPY AND DIAGNOSIS
Title (de)
C6ORF167 ALS ZIELGEN FÜR KREBSTHERAPIE UND -DIAGNOSE
Title (fr)
C6ORF167 COMME GÈNE CIBLE POUR LE TRAITEMENT ET LE DIAGNOSTIC DU CANCER
Publication
Application
Priority
- US 40192710 P 20100819
- US 37518410 P 20100819
- JP 2011004507 W 20110809
Abstract (en)
[origin: WO2012023259A1] Objective methods for diagnosing cancer or a predisposition to developing cancer, particularly lung cancer are described herein. The present invention provides a diagnostic method that utilizes the expression level of C6orf167 as an index of cancer. The present invention further provides methods of screening for therapeutic substances useful in the treatment of cancer, e.g. lung cancer. The invention further provides methods of inhibiting the cancer cell growth and either or both of treating and preventing cancer. The invention also features double stranded molecules against C6orf167 gene and an inhibitory polypeptide for NFKBIL2, as well as vector encoding them and compositions containing them.
IPC 8 full level
C12N 15/09 (2006.01); A61K 48/00 (2006.01); C07K 14/47 (2006.01); C12N 15/113 (2010.01); C12Q 1/68 (2006.01); G01N 33/574 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); C07K 14/4748 (2013.01); C12N 15/113 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57423 (2013.01); G01N 33/57484 (2013.01); A61K 38/00 (2013.01); C12N 2310/14 (2013.01); C12Q 2600/158 (2013.01); G01N 2500/04 (2013.01)
Citation (search report)
See references of WO 2012023259A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2012023259 A1 20120223; EP 2606132 A1 20130626; JP 2013542711 A 20131128
DOCDB simple family (application)
JP 2011004507 W 20110809; EP 11817909 A 20110809; JP 2013508310 A 20110809