EP 2614089 A1 20130717 - BIOTINYLATED PENTASACCHARIDES HAVING AN ANTITHROMBOTIC ACTIVITY AND IMPROVED METABOLIC STABILITY
Title (en)
BIOTINYLATED PENTASACCHARIDES HAVING AN ANTITHROMBOTIC ACTIVITY AND IMPROVED METABOLIC STABILITY
Title (de)
BIOTINYLIERTE PENTASACCHARIDE MIT ANTITHROMBOTISCHER WIRKUNG UND ERHÖHTER STOFFWECHSELSTABILITÄT
Title (fr)
PENTASACCHARIDES BIOTINYLES A ACTIVITE ANTITHROMBOTIQUE ET PRESENTANT UNE STABILITE METABOLIQUE AMELIOREE
Publication
Application
Priority
- FR 1154709 A 20110530
- FR 1057194 A 20100910
- FR 2011000498 W 20110909
Abstract (en)
[origin: WO2012042123A1] The invention relates to novel polysaccharides with an antithrombotic activity, having at least one covalent bond with biotin or a biotin derivative, characterised in that said covalent bond is resistant to metabolic cleavage and comprises a chain X selected from -O-, -N(R)-, -N(R)-CO- and -N(R')-CO-N(R")-, wherein R is an alkyl group and R' and R" are hydrogen atoms or alkyl groups. The invention also relates to the preparation and use of said polysaccharides in therapeutics.
IPC 8 full level
C08B 37/00 (2006.01); A61K 31/702 (2006.01); A61K 31/727 (2006.01); C07H 15/26 (2006.01)
CPC (source: EP US)
A61K 31/702 (2013.01 - EP US); A61K 31/727 (2013.01 - EP US); A61P 7/02 (2017.12 - EP); A61P 9/00 (2017.12 - EP); C07H 15/26 (2013.01 - US); C08B 37/0075 (2013.01 - EP US)
Citation (search report)
See references of WO 2012042123A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2012042123 A1 20120405; EP 2614089 A1 20130717; JP 2013537181 A 20130930; US 2013190268 A1 20130725
DOCDB simple family (application)
FR 2011000498 W 20110909; EP 11761652 A 20110909; JP 2013527656 A 20110909; US 201313790681 A 20130308