EP 2616075 A1 20130724 - METHODS OF CONVERTING A PATIENT'S TREATMENT REGIMEN FROM INTRAVENOUS ADMINISTRATION OF AN OPIOID TO ORAL CO-ADMINISTRATION OF MORPHINE AND OXYCODONE USING A DOSING ALGORITHM TO PROVIDE ANALGESIA
Title (en)
METHODS OF CONVERTING A PATIENT'S TREATMENT REGIMEN FROM INTRAVENOUS ADMINISTRATION OF AN OPIOID TO ORAL CO-ADMINISTRATION OF MORPHINE AND OXYCODONE USING A DOSING ALGORITHM TO PROVIDE ANALGESIA
Title (de)
VERFAHREN FÜR DEN ÜBERGANG EINES BEHANDLUNGSPLANS FÜR EINEN PATIENTEN VON DER INTRAVENÖSEN VERABREICHUNG EINES OPIOIDS ZUR GEMEINSAMEN ORALEN VERABREICHUNG VON MORPHIN UND OXYCODON ANHAND EINES DOSIERALGORITHMUS ZUR SCHMERZLINDERUNG
Title (fr)
MÉTHODES DE CONVERSION DU SCHÉMA DE TRAITEMENT D'UN PATIENT POUR LE FAIRE PASSER DE L'ADMINISTRATION D'UN OPIOÏDE PAR VOIE INTRAVEINEUSE À LA CO-ADMINISTRATION DE MORPHINE ET D'OXYCODONE PAR VOIE ORALE, BASÉES SUR UN ALGORITHME DE DOSAGE DESTINÉ À AVOIR UN EFFET ANALGÉSIQUE
Publication
Application
Priority
- US 88172810 A 20100914
- US 201113185016 A 20110718
- US 88167710 A 20100914
- US 2011051577 W 20110914
Abstract (en)
[origin: WO2012037239A1] A method of converting a treatment for pain comprising intravenous administration of opioids, to a treatment for pain comprising oral administration of a first dose of an immediate release mgrphine-oxycodone combination in patients in need of analgesia. The method may comprise (1) determining a four-hour average oral morphine equivalents, a one-hour average oral morphine equivalents, or determining a net average hourly inlravenous dose, and (2) orally administering to the patient a first dose of a morphine-oxycodone combination in a 3:2 ratio by weight every four to six hours. Also, a method of treating pain in patients who had been administered opioids intravenously, comprising using a dosing algorithm lo determine the first dose of the immediate release morphine-oxycodone combination.
IPC 8 full level
A61K 31/485 (2006.01); A61K 45/06 (2006.01); A61P 25/04 (2006.01)
CPC (source: EP)
A61K 31/485 (2013.01); A61K 45/06 (2013.01); A61P 25/04 (2017.12)
Citation (search report)
See references of WO 2012037239A1
Citation (examination)
- WEBSTER LYNN ET AL: "A double-blind, placebo-controlled study of dual-opioid treatment with the combination of morphine plus oxycodone in patients with acute postoperative", JOURNAL OF OPIOID MANAGEMENT: A MEDICAL JOURNAL OF PROPER AND ADEQUATE USE, WESTON MEDICAL PUBLISHING, LLC, US, vol. 6, no. 5, 1 September 2010 (2010-09-01), pages 329 - 340, XP009175574, ISSN: 1551-7489
- RICHARDS PATRICIA ET AL: "Analgesic and adverse effects of a fixed-ratio morphine-oxycodone combination (MoxDuo) in the treatment of postoperative pain", JOURNAL OF OPIOID MANAGEMENT: A MEDICAL JOURNAL OF PROPER AND ADEQUATE USE, WESTON MEDICAL PUBLISHING, LLC, US, vol. 7, no. 3, 1 May 2011 (2011-05-01), pages 217 - 228, XP009175579, ISSN: 1551-7489
- WEBSTER L ET AL: "Efficacy and tolerability of dual-opioid treatment with morphine plus oxycodone (MoxDuo(TM)) for acute postoperative pain", JOURNAL OF PAIN, SAUNDERS, PHILADELPHIA, PA, US, vol. 11, no. 4, 1 April 2010 (2010-04-01), pages S51, XP027094774, ISSN: 1526-5900, [retrieved on 20100401]
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2012037239 A1 20120322; AU 2011302137 A1 20130502; CA 2811285 A1 20120322; CN 103415291 A 20131127; EP 2616075 A1 20130724; JP 2013537232 A 20130930; ZA 201302585 B 20140528
DOCDB simple family (application)
US 2011051577 W 20110914; AU 2011302137 A 20110914; CA 2811285 A 20110914; CN 201180054571 A 20110914; EP 11776929 A 20110914; JP 2013529296 A 20110914; ZA 201302585 A 20130410