EP 2616477 A4 20141008 - 6-SUBSTITUTED DEMETHYL-ESTRADIOL DERIVATIVES AS ER-BETA AGONISTS
Title (en)
6-SUBSTITUTED DEMETHYL-ESTRADIOL DERIVATIVES AS ER-BETA AGONISTS
Title (de)
6-SUBSTITUIERTE DEMETHYL-ESTRADIOL-DERIVATE ALS ER-BETA-AGONISTEN
Title (fr)
DÉRIVÉS DE DIMÉTHYL-ESTRADIOL 6-SUBSTITUÉS À TITRE D'AGONISTES D'ER-BÊTA
Publication
Application
Priority
- US 38275210 P 20100914
- US 2011051608 W 20110914
Abstract (en)
[origin: US2012071455A1] Disclosed herein are 6-substituted 13-demethyl-estradiol derivatives as selective ERβ agonists. Also disclosed is a method for treating pain by administering these 6-substituted 13-demethyl-estradiol derivatives.
IPC 8 full level
C07J 1/00 (2006.01); A61K 31/565 (2006.01); A61P 25/04 (2006.01); C07J 31/00 (2006.01); C07J 41/00 (2006.01); C07J 17/00 (2006.01); C07J 51/00 (2006.01)
CPC (source: EP KR US)
A61K 31/56 (2013.01 - EP US); A61K 31/565 (2013.01 - KR); A61P 25/04 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07J 1/00 (2013.01 - KR); C07J 1/0059 (2013.01 - EP US); C07J 1/007 (2013.01 - EP US); C07J 31/006 (2013.01 - EP US); C07J 41/0016 (2013.01 - EP US); C07J 41/0044 (2013.01 - EP US); C07J 1/0074 (2013.01 - EP US); C07J 17/00 (2013.01 - EP US); C07J 51/00 (2013.01 - EP US)
Citation (search report)
- [Y] US 2008312202 A1 20081218 - YARGER JAMES [US]
- [Y] WO 2008067450 A2 20080605 - ENDECE LLC [US], et al
- [Y] US 6958327 B1 20051025 - HILLISCH ALEXANDER [DE], et al
- [Y] SHENGHONG XU ET AL: "17[beta]-Estradiol Activates Estrogen Receptor [beta]-Signalling and Inhibits Transient Receptor Potential Vanilloid Receptor 1 Activation by Capsaicin in Adult Rat Nociceptor Neurons", ENDOCRINOLOGY, vol. 149, no. 11, 1 November 2008 (2008-11-01), pages 5540 - 5548, XP055136528, ISSN: 0013-7227, DOI: 10.1210/en.2008-0278
- See references of WO 2012037261A2
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
US 2012071455 A1 20120322; AU 2011302065 A1 20130314; AU 2011302065 B2 20161201; BR 112013005843 A2 20191210; CA 2809639 A1 20120322; CA 2809639 C 20150630; CN 103097396 A 20130508; DK 2616477 T3 20170220; EP 2616477 A2 20130724; EP 2616477 A4 20141008; EP 2616477 B1 20161109; ES 2605960 T3 20170317; JP 2013540747 A 20131107; JP 2016138113 A 20160804; JP 5981434 B2 20160831; KR 101971128 B1 20190827; KR 20130138776 A 20131219; MX 2013002768 A 20130405; MX 343059 B 20161024; SG 188396 A1 20130430; US 2014315874 A1 20141023; US 9422324 B2 20160823; WO 2012037261 A2 20120322; WO 2012037261 A3 20120607
DOCDB simple family (application)
US 201113232798 A 20110914; AU 2011302065 A 20110914; BR 112013005843 A 20110914; CA 2809639 A 20110914; CN 201180044108 A 20110914; DK 11825878 T 20110914; EP 11825878 A 20110914; ES 11825878 T 20110914; JP 2013529299 A 20110914; JP 2016030043 A 20160219; KR 20137009269 A 20110914; MX 2013002768 A 20110914; SG 2013016159 A 20110914; US 2011051608 W 20110914; US 201414320110 A 20140630